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Testing the Lower Limits of CapNMR

Affordable HIGH SENSITIVITY Get spectra from a few micrograms of sample Take less from drug lead libraries Don't dilute your sample needlessly Excellent data quality and low noise Up to 100x faster than 5mm probes Boost utilization of existing magnets Get 1D proton spectra in a few minutes Get 2D correlation spectra in a few hours MicroFlow NMR rapidly pays for itself Eliminate cost of tubes Eliminate climbing of ladders Economical use of deuterated solvents Save sample preparation time and cost Minimize isotope reagent consumption And Much More!

CryoFlow NMR

At SMASH 2012, Protasis introduced, CryoFlow NMR, an exciting new way to load flowcell inserts for Bruker and Agilent cryogenically-cooled probes. In this work, we were able to clearly show the advantages of both native (same push solvent as the sample) and segmented flow (for 30uL active volume) flow inserts using a Bruker CryoFit* flowcell. Many pharma companies and university research groups now have cryoprobes and it is very quick and easy to drop a flowcell insert into them to enable plate/vial automation using One-Minute NMR. In particular, this is a new alternative to CapNMR microcoil flowcells for larger-volume life science applications.

Now One-Minute NMR works with flowcell inserts for Bruker & Agilent cold probes!

* CryoFIT and Cryoprobes are trademarks of Bruker Biospin Ltd.