{"id":424,"date":"2014-05-17T05:27:49","date_gmt":"2014-05-17T05:27:49","guid":{"rendered":"http:\/\/protasis.net\/blog2014\/?page_id=424"},"modified":"2014-07-13T06:37:41","modified_gmt":"2014-07-13T06:37:41","slug":"capnmr-icg-probe","status":"publish","type":"page","link":"http:\/\/protasis.net\/blog2014\/?page_id=424","title":{"rendered":"Advantages of microcoils"},"content":{"rendered":"<div class=\"flex_column av_two_third  flex_column_div first  \" ><section class=\"av_textblock_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock '   itemprop=\"text\" ><h2>Advantages of Microcoils<\/h2>\n<p><em><strong>Sensitivity, Simplicity and Economy<\/strong><\/em><\/p>\n<\/div><\/section><\/div>\n<div class=\"flex_column av_one_third  flex_column_div   \" ><div class='avia-button-wrap avia-button-center '><a href='' class='avia-button  avia-icon_select-yes-left-icon avia-color-theme-color avia-size-large avia-position-center '   ><span class='avia_button_icon avia_button_icon_left ' aria-hidden='true' data-av_icon='\ue86d' data-av_iconfont='entypo-fontello'><\/span><span class='avia_iconbox_title' >Catalog Page<\/span><\/a><\/div><\/div>\n<div class=\"flex_column av_two_third  flex_column_div first  \" ><div  data-autoplay='false'  data-interval='20'  data-animation='slide'  data-show_slide_delay='30'  class='avia-content-slider-element-container avia-content-slider-element-slider avia-content-slider avia-smallarrow-slider avia-content-slider-active avia-content-slider1 avia-content-slider-odd ' ><div class='avia-smallarrow-slider-heading '><div class='new-special-heading'><h3>SENSITIVITY<\/h3><\/div><div class='avia-slideshow-arrows avia-slideshow-controls'><a href='#prev' class='prev-slide' aria-hidden='true' data-av_icon='\ue87c' data-av_iconfont='entypo-fontello'>Previous<\/a><a href='#next' class='next-slide' aria-hidden='true' data-av_icon='\ue87d' data-av_iconfont='entypo-fontello'>Next<\/a><\/div><\/div><div class='avia-content-slider-inner'><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-1 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Get Spectra From as Little as 1 Microgram of Sample<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p style=\"word-spacing: 0px; margin-left: 4px;\" align=\"left\"><span style=\"color: #666666; font-family: Tahoma;\"><span style=\"font-size: small;\">Microcoils<\/span><span style=\"font-size: small;\"> provide greater sensitivity than conventional NMR detector coils to receiving the NMR magnetization signal from small amounts of sample.\u00a0 This is explained by considering that the process of signal induction in the windings of the detection coil is more efficient when the windings tightly couple to the sample.\u00a0 <span lang=\"EN\" style=\"line-height: 150%;\">Microcoils employ a solenoidal geometry, which is a tightly-wound, multi-turn structure in which the RF (B1) field is highly focused in the interior region of interest (the region where the NMR flowcell is positioned in the CapNMR probe.)\u00a0 In contrast, the RF coils employed in conventional tube-based probes are typically of the saddle coil (or Helmholtz) variety.\u00a0 Saddle coils are essentially a loosely wound, 2-turn solenoid, shaped to accommodate the passage of an NMR tube between the two turns of the coil.\u00a0 This compromise in design is made to facilitate sample change, where tube insertion and replacement is required.\u00a0 The B1 field must remain perpendicular to the main (B0) magnet field, and a multi-turn solenoid would not permit tubes to be loaded from the top of the magnet into the coil.\u00a0 The loosely coupled saddle coil design results in a sensitivity loss of approximately 2-3-fold compared to a solenoid of comparable size (Hoult and Richards, <i>J. Mag Res.<\/i> 24, 71, 1976).\u00a0 Smaller solenoids are more mass-sensitive than larger solenoids, resulting in an additional scaling factor that is approximately proportional to coil diameter.\u00a0 The result is that a 1mm-scale solenoidal microcoil is approximately 10-fold more mass-sensitive than a conventional-scale saddle coil.<\/span>\u00a0 Microcoils enable you to use less sample, while providing the same spectral information obtained using a larger coil.\u00a0 <\/span><span lang=\"EN\" style=\"line-height: 150%; font-weight: bold;\"><span style=\"font-size: small;\">This means that you can save time and money by using less and from the ability to get the same information from micrograms (or less) of sample.<\/span><\/span><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-2 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Low Power Allows Broadband Spectra<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #666666; font-family: Tahoma; font-size: small;\">A second consequence of more efficient signal induction with microcoils is that microcoils require far less power to excite the NMR sample (e.g. the transmitter power required to obtain a desired value of t<sub>90<\/sub>).\u00a0 Whereas conventional probes typically utilize 100\u00a0W \u2013 300\u00a0W amplifiers, microcoils use only a fraction of this power, typically 1\u00a0W.\u00a0 The \u201cspare power\u201d available provides an ability to excite a far greater chemical shift bandwidth than is possible with larger coils, where typically both the coil and amplifier begin to exhibit non-linearities and voltage arcing at the higher power levels.\u00a0 Also, the available power with microcoils permits cleaner pulses and longer, more complicated pulse sequences to be deployed by the ability to maintain t<sub>90<\/sub> to virtually any reasonable desired value.\u00a0 Finally, the greater surface-to-volume ratio at the capillary scale provides more efficient thermal transfer of heat from the sample to the surrounding walls of the capillary, <strong>meaning that the NMR experiment can be performed with less concern of heating the sample.<\/strong><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-3 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >High Resolution<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p style=\"margin-left: 4px;\" align=\"left\"><span style=\"font-family: Tahoma;\"><span style=\"color: #666666; font-size: small;\">NMR is a magnetic field sensing technique, and consequently, the design of an NMR probe must by definition take into account the perturbing effect that the detection elements will have on the (otherwise homogeneous) magnetic field (B<sub>0<\/sub>).\u00a0 In conventional tube probes, the container that holds the sample is removed and re-inserted with the sample each time a new sample is introduced.\u00a0 Mechanical tolerances (air gaps) are required to facilitate tube loading, and the introduction of a new container with each new sample means that tube-to-tube disparities must be compensated as part of the shimming process.\u00a0 Protasis probes utilize flow technology to introduce the sample.\u00a0 This enables the use of a consistent sample containment geometry (the NMR flowcell) that does not change from sample-to-sample.\u00a0 In <\/span><\/span> <span style=\"color: #666666; font-family: Tahoma;\"><span style=\"font-size: small;\"> turn, this enables a design approach where the mechanical structure of the flowcell can be optimized for magnetic match with less variability experiment-to-experiment, resulting in higher resolution and greater S\/N than would be possible at this size scale if a more mechanically-complicated, tube replacement geometry were employed for sample loading.\u00a0 <\/span><b> <span style=\"font-size: small;\">CapNMR probes generally do not require re-shimming from sample-to-sample, provided that a consistent solvent is employed.<\/span><\/b><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-4 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >High Fill Factor and High Observe Factor<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #666666; font-family: Tahoma; font-size: small;\">The ability to design the CapNMR probe using a consistent sample containment geometry (the NMR flowcell) that does not change with each introduction of a new sample provides a geometry where the RF detection coil can be tightly coupled to the sample.\u00a0 Contrary to tube-based approaches, where the RF coil must be somewhat larger than the tube to permit mechanical clearance for removal and re-insertion of a new tube for each new sample over the course of thousands of sample changes, the microflow approach used with CapNMR probes facilitates winding the coil directly onto the NMR flowcell (for high fill factor), and the use of an extremely thin capillary wall that would not survive the mechanical rigor of the robotic, tube removal and re-insertion approach.\u00a0 Further, the coil and flowcell geometry can be designed so that the RF field produced by the coil captures a maximal amount of the flowcell (and sample) volume (for high observe factor).\u00a0 Together, these attributes result in optimal signal detection from your sample, and greater S\/N.<\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-5 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Low Noise \/ Clean Baselines<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #666666; font-size: small;\"><span lang=\"EN\" style=\"font-family: Tahoma;\">Stated above, the tightly coupled and defined RF field produced by the millimeter-scale microcoils results in higher signal induction and greater mass-detection sensitivity.\u00a0 A further benefit of small scale and the use of solenoidal microcoils is that the RF fields are produced<\/span><span style=\"font-family: Tahoma;\"><span lang=\"EN\" style=\"line-height: 150%;\"> in a manner that inherently provides cleaner baselines and fewer unwanted materials artifacts.\u00a0 Explained above, the solenoid is a tightly-wound, multi-turn magnetic field sensor in which the RF (B1) field is highly focused in the interior region of interest (the region where the NMR flowcell is positioned in the CapNMR probe,) whereas in contrast, saddle coils are typically designed to be less tightly coupled, to provide mechanical clearances to accommodate the passage of an NMR tube into and out of the coil at each sample change.\u00a0 The \u201cstray\u201d fields (e.g. fields that extend outside the region containing the sample) are significantly greater when employing larger coils that are more loosely coupled to the sample.\u00a0 These fields penetrate other components (electrical components, mechanical structures, etc.) of the probe, and if protons are present (most materials are protonated), result in baseline artifacts that are virtually impossible to eliminate.\u00a0 The use of a small solenoidal microcoil means that relative to the size of the coil, the other components of the probe are far more distant than with larger RF coils.\u00a0 <b>The result is less signal from unwanted sources, flater baselines, and cleaner spectra.<\/b>\u00a0\u00a0 <b>This is particularly important when considering low mass samples, where two probes with the same mass sensitivity can provide drastically different NMR spectral performance<\/b>.<\/span><\/span><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-6 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >High Signal-to-Solvent Ratio<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #666666;\"><span style=\"font-family: Tahoma;\"><span style=\"font-size: small;\">Significant effort has been expended in the past decade to incorporate means of chemical purification prior to NMR detection, in an attempt to isolate the analyte of interest and to eliminate unwanted \u201cnoise\u201d from the NMR spectrum. \u00a0Of the wide array of analytical methods that have been employed, the most popular NMR hyphenation has involved high performance liquid chromatography (HPLC).\u00a0 HPLC columns have been used to separate complex mixtures in order to isolate specific analytes for subsequent NMR investigation, and less aggressive forms of solid phase media (e.g. solid phase extraction cartridges) have been employed to concentrate analytes of interest and thereby maximize the desired <\/span><\/span> <span style=\"font-family: Tahoma; font-size: small;\"><span lang=\"EN\">(analyte) signal relative to the unwanted (solvent) signal in the NMR spectrum, i.e. to provide a high signal-to-solvent ratio.\u00a0 Considering the large proton abundance (typically molar concentration) in solvents relative to that (typically millimolar or less) in analytes, concentration of the analyte minimizes the challenges associated with solvent suppression and generally provides cleaner NMR baselines.\u00a0 The same concept applies to the condition of small mass analysis.\u00a0 While some larger-volume (e.g. cryo technology) probes boast of comparable mass sensitivity to microcoils, the use of such probes requires that the small analyte mass be dissolved into a relatively large volume of solvent.\u00a0 This approach results in a low signal-to-solvent ratio, and generally results in a NMR spectrum that is complicated by solvent and impurity artifacts.\u00a0 While the use of deuterated solvents and ultra-pure reagents helps to reduce unwanted artifacts, this truth applies equally to microcoils and larger volume applications.\u00a0 The simplest and most efficient approach is to maintain a high analtye concentration and to utilize clean, deuterated solvents.\u00a0 This is the approach used by the CapNMR probe.<\/span><\/span><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-7 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Excellent Salt Tolerance<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #0000aa; font-size: medium;\"><span style=\"font-family: Arial;\"><span style=\"color: #666666; font-size: small;\"><span style=\"font-family: Tahoma;\">Small coils are typically more tolerant to variations in sample conductivity (e.g. salt) than are larger coils.\u00a0 While this is not a rationale for comparing the absolute S\/N of one probe technology against another (such comparisons should be made using the sensitivity arguments explained previously), greater salt tolerance does imply that the degree of intervention required to adjust (e.g. tune, shim) the probe between sample runs is less, and that the S\/N obtained using a salty sample and a microcoil probe will be closer to the S\/N obtained using a non-salty sample.\u00a0 This translates to ease of use and greater experimental consistency for the spectroscopist, faster analysis due to less need for shimming (and consequently reduced shim settling times) and re-tuning between samples.<\/span><\/span><\/span><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-8 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Rapid Recovery from Steep Solvent Gradients<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #666666; font-family: Tahoma; font-size: small;\">NMR is inherently sensitive to the magnetic environment of the sample, and consequently to the composition of the sample.\u00a0 Hyphenated LC-NMR applications have demonstrated that compositional variations (e.g. solvent gradients) result in time-dependent magnetic field perturbations that can destroy spin coherence.\u00a0 The diffusion-based process of re-stabilization toward equilibrium is greatly enhanced in geometries that possess a large surface-to-volume ratio.\u00a0 By definition, this means that smaller geometries are better suited to rapid restoration of equilibrium conditions than are larger geometries.\u00a0 This means that programmed variations in flow conditions (e.g. solvent gradient LC runs) as well as unintentional variations (solvent\/sample mismatches) can both be accommodated more quickly with the CapNMR probe, resulting in shorter wait periods for you to get the data you desire.\u00a0 Less time, less money, and greater sensitivity performance, all in a simple-to-use package, make microflow NMR the technique of choice that many are turning to for addressing their application needs.<\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-9 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >High Magnetic Field Gradients<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"font-family: Tahoma;\"><span style=\"color: #666666; font-size: small;\">The enhanced magnetic field performance of smaller coils is valid for small gradient coils as well.\u00a0 Applicable CapNMR probe models employ a small z-gradient coil that requires very little power (10-20% of full gradient driver power, typ.) to produce standard field gradient values (40-80 G\/cm), and can be operated at higher powers to reliably produce gradient strengths of hundreds of G\/cm for diffusion and other gradient-intensive spectroscopy applications.\u00a0 Further, the use of a smaller coil geometry means that the fields produced are better confined and have less interaction with the magnet and surrounding structure.\u00a0 This means less eddy currents and faster settling times, with less demand for complicated shielding circuitry.\u00a0 Simple, effective, and efficient \u2013 the microflow way.<\/span><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-10 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Excellent Multi-Nuclear Sensitivity<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #666666; font-family: Tahoma; font-size: small;\">RF design constraints are simpler to manage at smaller size scale.\u00a0 This is obvious from the complexity that has been achieved in modern desktop computers, where miniaturization and integration have provided functionality that far surpasses that of large, mainframe computers of decades prior, at a fraction of the cost.\u00a0 The electrical properties of microcoils make them amenable to novel forms of RF isolation that is not feasible at larger size scales, making it possible to include multiple nuclear frequencies on the microcoil.\u00a0 This is contrary to conventional heteronuclear probes, where \u201cinner\u201d and \u201couter\u201d coils are employed, and where sacrifices in sensitivity are made to \u201couter\u201d coil nuclei and to minimize the number of nuclei present on the \u201cinner\u201d detection coil.\u00a0 With microcoils, all nuclei are channeled to the primary coil, and reception can be accomplished with negligible penalty in 1H sensitivity, while supporting alternative nuclei (e.g.. 13C) on the same coil.\u00a0 One high quality coil for all nuclei, used for both transmission and reception \u2013 this is CapNMR sensitivity, simplicity, and economy working together.<\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-11 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Excellent Thermal Stability<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #666666; font-family: Tahoma; font-size: small;\"><span lang=\"EN\" style=\"line-height: 150%;\">Thermal gradients are inherently smaller and easier to manage in small spaces relative to large spaces.\u00a0 This works to advantage in the CapNMR probe, where thermostating your sample can be accomplished simply and efficiently, with excellent NMR results.\u00a0 This means less thermal settling time, and better results, faster.<\/span><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-12 slide-parity-odd  post-entry-last  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Efficient Sample Delivery and Recovery<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span lang=\"EN\" style=\"font-family: Tahoma;\"><span style=\"color: #666666; font-size: small;\">Obtaining a high signal-to-noise ratio requires a probe that is highly sensitive, and a means for efficient and effective transfer of sample to the detection region of the probe without compromise to the condition of the sample.\u00a0 Capillary scale fluidics are far superior to conventional-scale transfer tubing in their ability to accurately, reproducibility, and reliably transfer samples to the probe.\u00a0 Detrimental forces of nature that lead to peak broadening and dilution in conventional-scale tubing are virtually eliminated at the capillary scale.\u00a0 This is particularly important in NMR, where often the sample preparation and control instrumentation are physically distant from the magnet, to preserve the 5G safety line.\u00a0 Microflow NMR means that you can prepare your sample, and inject it reliably in a format that is not diminished as it passes through the transfer line.\u00a0\u00a0 Simple, economic operation, with high performance results \u2013 the microflow way.<\/span><\/span><\/p>\n<\/div><\/section><\/div><\/div><\/div><\/div>\n<div class=\"flex_column av_one_third  flex_column_div   \" ><div  data-autoplay='true'  data-interval='10'  data-animation='slide'  data-show_slide_delay='30'  class='avia-content-slider-element-container avia-content-slider-element-slider avia-content-slider avia-smallarrow-slider avia-content-slider-active avia-content-slider2 avia-content-slider-odd ' ><div class='avia-smallarrow-slider-heading '><div class='new-special-heading'><h3>Innovating microNMR<\/h3><\/div><div class='avia-slideshow-dots avia-slideshow-controls'><a href='#1' class='goto-slide active' >1<\/a><a href='#2' class='goto-slide ' >2<\/a><\/div><\/div><div class='avia-content-slider-inner'><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-1 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >CapNMR ICG Probe<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><a href=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/VerticalProbe-001-320W-500x500.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"alignleft wp-image-1214 size-full\" src=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/VerticalProbe-001-320W-500x500.jpg\" alt=\"VerticalProbe-001-320W-500x500\" width=\"500\" height=\"500\" srcset=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/VerticalProbe-001-320W-500x500.jpg 500w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/VerticalProbe-001-320W-500x500-80x80.jpg 80w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/VerticalProbe-001-320W-500x500-300x300.jpg 300w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/VerticalProbe-001-320W-500x500-36x36.jpg 36w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/VerticalProbe-001-320W-500x500-180x180.jpg 180w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/VerticalProbe-001-320W-500x500-120x120.jpg 120w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/VerticalProbe-001-320W-500x500-450x450.jpg 450w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/a><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-2 slide-parity-odd  post-entry-last  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Our Analytical Chemistry Cover<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><a href=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"alignleft size-portfolio wp-image-54\" src=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500-495x400.jpg\" alt=\"image006-500x500\" width=\"495\" height=\"400\" \/><\/a><\/p>\n<\/div><\/section><\/div><\/div><\/div><\/div>\n<div class=\"flex_column av_two_third  flex_column_div first  \" ><div  data-autoplay='false'  data-interval='20'  data-animation='slide'  data-show_slide_delay='30'  class='avia-content-slider-element-container avia-content-slider-element-slider avia-content-slider avia-smallarrow-slider avia-content-slider-active avia-content-slider3 avia-content-slider-odd ' ><div class='avia-smallarrow-slider-heading '><div class='new-special-heading'><h3>SIMPLICITY<\/h3><\/div><div class='avia-slideshow-arrows avia-slideshow-controls'><a href='#prev' class='prev-slide' aria-hidden='true' data-av_icon='\ue87c' data-av_iconfont='entypo-fontello'>Previous<\/a><a href='#next' class='next-slide' aria-hidden='true' data-av_icon='\ue87d' data-av_iconfont='entypo-fontello'>Next<\/a><\/div><\/div><div class='avia-content-slider-inner'><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-1 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Sensible Sensitivity<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p style=\"word-spacing: 0px; margin-left: 4px;\" align=\"left\"><span style=\"color: #666666; font-family: Tahoma;\"><span lang=\"EN\" style=\"line-height: 150%;\"><span style=\"font-size: small;\"><span lang=\"EN\"><span style=\"color: #666666; font-family: Tahoma; font-size: small;\">Protasis CapNMR probes achieve high mass sensitivity by tightly conforming the radiofrequency detection coil to the sample, for high fill factor.\u00a0 Since the sensitivity advantage is achieved through size reduction, the RF coil can be maintained at room-temperature, thereby making unnecessary the use of cooling systems and ancillary supporting platforms.\u00a0 The probe is easily inserted into the NMR magnet in a matter of minutes, and shimming and tuning are rapidly performed.\u00a0 Simplicity of design also means that the probe can be operated for extended periods of time with minimal maintenance, employing rinse and cleaning protocols that can be easily performed in your laboratory.\u00a0 In the unlikely event that the probe require return-to-factory service, diagnosis and repair can be rapidly completed.\u00a0 Simple design, simple operation, superior results \u2013 the CapNMR way.<\/span><\/span><\/span><\/span><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-2 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Easy shimming<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #666666;\"><span style=\"font-family: Tahoma;\"><span lang=\"EN\"><span style=\"font-size: small;\">Protasis CapNMR probes employ small-volume NMR flowcells (5 and 10\u00a0<\/span><\/span><\/span><span style=\"font-size: small;\"><span lang=\"EN\" style=\"font-family: Tahoma;\">m<\/span><\/span><span style=\"font-family: Tahoma;\"><span lang=\"EN\"><span style=\"font-size: small;\">L) into which the sample is loaded for NMR analysis.\u00a0 Not only is less sample required for analysis than is required in larger-volume probes, but an added benefit of the small size scale is that the spatial region over which magnetic field (B0) homogeneity is required (for high spectral resolution) is greatly reduced as well.\u00a0 This in turn means that the challenges of shimming are significantly reduced over the case of larger volume samples, and consequently, the process of shimming is greatly simplified.\u00a0 In general, CapNMR probes shim in a matter of minutes using a small fraction (&lt;\u00a07, typical) channels of the total available shim system.\u00a0 Shimming between samples is typically not required \u2013 in fact, once shimmed, the probe typically does not require re-shimming except for solvent change or when re-installing the probe after removal from the magnet.\u00a0 This translates to easier usage, less time adjusting, and more time for taking data.<\/span><\/span><\/span><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-3 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Easy Tuning<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #666666;\"> <span lang=\"EN\" style=\"font-size: 10pt; font-family: Tahoma;\">Protasis probes employ a small solenoidal microcoil for radiofrequency detection.\u00a0 This coil is designed and manufactured to remain in intimate contact with the outer surface of the NMR flowcell.\u00a0 Contrary to tube-based probes where sufficient tolerance must be maintained to facilitate tube removal and insertion, the only material changing from sample-to-sample in Protasis probes is the sample itself.\u00a0 RF tuning is easily performed using standard \u201ctune\u201d and \u201cmatch\u201d wands, and due to the minimal perturbation experienced by the microcoil from sample-to-sample, does not typically require re<\/span><\/span><span style=\"color: #666666; font-family: Tahoma; font-size: small;\"><span lang=\"EN\">adjustment except when a new solvent is introduced.\u00a0 This means less worry for you, less time required for probe adjustment, and more time to focus on what is important \u2013 your sample and your data.<\/span><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-4 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Use All of Your Standard NMR Methods<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #666666; font-family: Tahoma; font-size: small;\"><span lang=\"EN\">The Protasis CapNMR probe utilizes an RF coil that behaves virtually the same as a larger RF coil from a room-temperature probe.\u00a0 This means that your RF pulse sequences and NMR parameters can translate immediately to the CapNMR probe.\u00a0 In fact, the only adjustment that is required is a reduction of transmitted RF (and lock) power, and in the case of gradient experiments, a reduction of the power supplied to the gradient coil.\u00a0 These adjustments are fully explained in the CapNMR manual, and involve a common scaling factor that is applied to each pulse sequence.<\/span><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-5 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Sample Management Made Simple<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p style=\"margin-left: 8.85pt;\"><span style=\"color: #666666;\"><span style=\"font-family: Tahoma;\"> <span lang=\"EN\"><span style=\"font-size: small;\">Protasis offers a range of sample management options for loading samples into the CapNMR probe.\u00a0 Customers with fewer numbers of samples, who are generally interested in documentation or publication (external or internal to the organization) of results can benefit from the Protasis Citation<\/span><\/span><\/span><span style=\"font-size: small;\"><span lang=\"EN\" style=\"font-family: Tahoma;\">\u00d4<\/span><\/span><span style=\"font-family: Tahoma;\"><span lang=\"EN\"><span style=\"font-size: small;\"> platform.\u00a0 Samples are simply and easily loaded manually, from a syringe, into an injection loop.\u00a0 When you are ready to load the sample into the probe, simply push a button.\u00a0 The sample travels a pre-calibrated distance under tightly controlled flowrate and stops automatically in the center of the NMR flowcell.\u00a0 Sample removal (and optional retrieval) is facilitated by pushing the button a second time.\u00a0 Customers with greater interest in automation can use the CTC (Leap Technologies) liquid handler to operate the syringe and inject the sample into an injection loop, followed by loading into the probe, all under Protasis One-Minute NMR automation control.\u00a0 Data storage and retrieval is readily facilitated by One-Minute MR as well.\u00a0 This state-of-the-art software runs from any pc or workstation capable of running a web browser, and interfaces to common industry structure confirmation packages.\u00a0 Sensors on both Citation and One-Minute NMR systems inform the user in the unlikely event of trouble during sample injection, and also offer reminders with regard to filter change and system maintenance.\u00a0 New features and capabilities are being added continually to enhance the functionality of the Protasis sample management systems and to provide new solutions for our customers.\u00a0 Call us today with your specific need or special request!<\/span><\/span><\/span><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-6 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Compatible with Varian, Bruker and JEOL<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p>Protasis has more than 200 installations on all makes and models of NMR magnets and spectromters from 200 MHz up to 800 MHz.<\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-7 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Easy Sample Recovery<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #666666; font-family: Tahoma; font-size: small;\"><span lang=\"EN\">Conventional (tube-based) probe systems typically employ a flow-loading system up-stream of the NMR analysis to load the sample from well plates or vials into the NMR probe.\u00a0 The tube is then robotically loaded into the probe, and upon completion of the experiment, robotically removed to a holding rack.\u00a0 Replacement into the wellplate or vial may be required in some instances.\u00a0 Protasis CapNMR probes utilize uni-directional flow to accurately position the sample in the NMR flowcell, and upon completion of the experiment, to remove the sample from the flowcell and optionally return the sample to the well or vial from which it came (or a different well or vial of user choice).\u00a0 This is all accomplished via accurate and reliable flow, without the need for robotic intervention or mechanical change to the detection elements of the probe.\u00a0 Sample return is easily enabled via a side-port on the injection syringe.\u00a0 Protasis programmability means that you can instruct the sample management system to perform sample return automatically for thousands of samples each day.\u00a0 Operational ease, through simplicity of design\u2026<\/span><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-8 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Simple, Smooth Flowpath<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #666666;\"><span style=\"font-family: Tahoma;\"><span lang=\"EN\"><span style=\"font-size: small;\">Protasis probes and fluidics systems employ highly accurate and tightly calibrated capillary-scale transfer lines made of fused silica or FEP Teflon<\/span><\/span><\/span><span style=\"font-size: small;\"><span lang=\"EN\" style=\"font-family: Tahoma;\">\u00d2<\/span><\/span><span style=\"font-family: Tahoma;\"><span lang=\"EN\"><span style=\"font-size: small;\"> for transfer of the sample from the point of injection into the probe.\u00a0 These lines provide a cleanly swept flowpath, and preserve sample concentration and volume as the sample traverses several meters of length from the point of injection to the NMR flowcell.\u00a0 This translates to optimal performance and high signal-to-noise ratio, using a system that is easy to maintain and easy to understand.\u00a0 At Protasis, we don\u2019t believe that high performance requires high technological complexity.\u00a0 Rather, we believe that the simplicity of our design offers operational advantages that lead to functional benefits and enable more complicated experimental protocols to be successfully applied.\u00a0 Said differently, we think that the emphasis on complexity should rest with how our instrumentation enables your complicated experimental protocols, and not with the operation or maintenance of the instrument itself.<\/span><\/span><\/span><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-9 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Compatible with 200 MHz \u2013 800 MHz Field Strengths<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #666666;\"><span lang=\"EN\" style=\"font-family: Tahoma;\"> <span style=\"font-size: small;\">Protasis probes are designed to function in the range of field strengths most popular to NMR.\u00a0 The simple radiofrequency (RF) design makes it possible to provide multiple-resonances for multi-nuclear detection on a single coil, providing mass sensitivity advantage for all nuclei <\/span><\/span> <span style=\"font-family: Tahoma; font-size: small;\"><span lang=\"EN\">relative to what would be achieved when \u201cinside-outside\u201d multi-coil geometries are required.\u00a0 The same simplicity rules and ease-of-shimming\/ease-of-tuning apply to the higher field strengths as well.<\/span><\/span><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-10 slide-parity-odd  post-entry-last  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Excellent Solvent Compatibility<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #666666;\"><span style=\"font-family: Tahoma;\"><span lang=\"EN\"><span style=\"font-size: small;\">The choice of fused silica and FEP Teflon<\/span><\/span><\/span><span style=\"font-size: small;\"><span lang=\"EN\" style=\"font-family: Tahoma;\">\u00d2<\/span><\/span><span style=\"font-family: Tahoma;\"><span lang=\"EN\"><span style=\"font-size: small;\"> for the wetted surfaces of the probe and fluidics system means that virtually all popular NMR solvents are supported in Protasis CapNMR probes. \u00a0Further, the ability to utilize (and subsequently dispose of) extremely small volumes of solvents and reagents means that you can be more judicious in your choice of optimized (and more costly) solvents, including the use of fully-deuterated solvents.\u00a0 This translates to less need for solvent suppression, and greater focus on the signal from the analyte of interest.\u00a0 Simple and effective \u2013 the CapNMR advantage.<\/span><\/span><\/span><\/span><\/p>\n<\/div><\/section><\/div><\/div><\/div><\/div>\n<div class=\"flex_column av_one_third  flex_column_div   \" ><div  data-autoplay='true'  data-interval='10'  data-animation='slide'  data-show_slide_delay='30'  class='avia-content-slider-element-container avia-content-slider-element-slider avia-content-slider avia-smallarrow-slider avia-content-slider-active avia-content-slider4 avia-content-slider-odd ' ><div class='avia-smallarrow-slider-heading '><div class='new-special-heading'><h3>Vendor Flexibility<\/h3><\/div><div class='avia-slideshow-dots avia-slideshow-controls'><a href='#1' class='goto-slide active' >1<\/a><a href='#2' class='goto-slide ' >2<\/a><a href='#3' class='goto-slide ' >3<\/a><\/div><\/div><div class='avia-content-slider-inner'><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-1 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Bruker 400 MHz in Medicinal Chemistry<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><div id=\"attachment_997\" style=\"width: 505px\" class=\"wp-caption alignleft\"><a href=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/IMG_0809.jpg\"><img aria-describedby=\"caption-attachment-997\" decoding=\"async\" loading=\"lazy\" class=\"size-portfolio wp-image-997\" src=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/IMG_0809-495x400.jpg\" alt=\"One-Minute NMR on Bruker 400MHz\" width=\"495\" height=\"400\" srcset=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/IMG_0809-495x400.jpg 495w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/IMG_0809-710x575.jpg 710w\" sizes=\"(max-width: 495px) 100vw, 495px\" \/><\/a><p id=\"caption-attachment-997\" class=\"wp-caption-text\">One-Minute NMR on Bruker 400MHz<\/p><\/div>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-2 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >One-Minute NMR (Enclosed) on Varian 400<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><a href=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/MedChem-St.Louis-Front-001.png\"><img decoding=\"async\" loading=\"lazy\" class=\"alignleft wp-image-1003 size-portfolio\" src=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/MedChem-St.Louis-Front-001-495x400.png\" alt=\"MedChem-St.Louis-Front-001\" width=\"495\" height=\"400\" \/><\/a><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-3 slide-parity-odd  post-entry-last  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >One-Minute NMR on Small Footprint SS Cart<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><a href=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/Workcenter-SS-Case-Cart-Amgen-600MHz-Front-600W-002.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"alignleft wp-image-1188 size-portfolio\" src=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/Workcenter-SS-Case-Cart-Amgen-600MHz-Front-600W-002-495x400.jpg\" alt=\"Workcenter SS Case Cart - Amgen 600MHz - Front - 600W - 002\" width=\"495\" height=\"400\" \/><\/a><\/p>\n<\/div><\/section><\/div><\/div><\/div><\/div>\n<div class=\"flex_column av_two_third  flex_column_div first  \" ><div  data-autoplay='false'  data-interval='20'  data-animation='slide'  data-show_slide_delay='30'  class='avia-content-slider-element-container avia-content-slider-element-slider avia-content-slider avia-smallarrow-slider avia-content-slider-active avia-content-slider5 avia-content-slider-odd ' ><div class='avia-smallarrow-slider-heading '><div class='new-special-heading'><h3>ECONOMY<\/h3><\/div><div class='avia-slideshow-arrows avia-slideshow-controls'><a href='#prev' class='prev-slide' aria-hidden='true' data-av_icon='\ue87c' data-av_iconfont='entypo-fontello'>Previous<\/a><a href='#next' class='next-slide' aria-hidden='true' data-av_icon='\ue87d' data-av_iconfont='entypo-fontello'>Next<\/a><\/div><\/div><div class='avia-content-slider-inner'><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-1 slide-parity-odd  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >More Information, Less Sample<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"font-family: Tahoma;\"><span lang=\"EN\"><span style=\"color: #666666; font-size: small;\">The economics and efficiency of \u201cdoing more with less\u201d are well understood across a broad array of scientific disciplines and technology platforms.\u00a0 Fundamental to the core mission of\u00a0 Protasis\/MRM is the transfer of innovative application methodologies and component technologies from analytical techniques where miniaturization has been shown to provide clear advantage.\u00a0 Capillary fluidic transport, tightly controlled fluidic pumps and valves, miniaturized detectors, and web-based automation and control software are all components and feature attributes borrowed from complementary techniques and applied to NMR to achieve similar advantage.\u00a0 NMR has until this time remained historically rooted in tube-based samples and the need for milliliters and milligrams of material.\u00a0 The ability to analyze microliters and micrograms means that you can focus your time on doing more NMR analysis without waiting for additional sample prep.\u00a0 It means that you can more quickly analyze your synthesis product to make assessments earlier in the process.\u00a0\u00a0 It means that with less time for expression you can understand basic behavior attributes of your proteins so you can intelligently direct financial resources to the candidates that merit further analysis.\u00a0 It means that you can time-track the biofluid data of one mouse rather than an ensemble average.\u00a0 It means that you can accept microplate and microvial sample media formats compatible with other techniques so that NMR can added to the measurement chain without precondition for additional sample work-up.\u00a0 It means that you might avoid the technician and quality control resources required to reconstitute to a previous format by simply not being required to \u201cgive back\u201d the 5<\/span><\/span><\/span><span style=\"color: #666666;\"><span style=\"font-size: small;\"><span style=\"font-family: Tahoma;\">\u00a0<\/span><span style=\"font-family: Tahoma;\">m<\/span><span style=\"font-family: Tahoma;\">L you injected.\u00a0 <\/span><\/span><span style=\"font-family: Tahoma;\"><span lang=\"EN\"><span style=\"font-size: small;\"> Simply put, it means that you can get information more quickly, information you need to make decisions to direct your resources more wisely.\u00a0 It\u2019s the economy of small size scale, and it\u2019s a microflow CapNMR advantage.<\/span><\/span><\/span><\/span><\/p>\n<p style=\"word-spacing: 0px; margin-left: 4px;\" align=\"left\"><span style=\"color: #666666; font-family: Tahoma;\"><span lang=\"EN\" style=\"line-height: 150%; font-weight: bold;\"><span style=\"font-size: small;\">\u00a0<\/span><\/span><\/span><\/p>\n<\/div><\/section><\/div><div class='slide-entry-wrap'><section class='slide-entry flex_column post-entry slide-entry-overview slide-loop-2 slide-parity-odd  post-entry-last  av_fullwidth first'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" >Consume Less Solvent<\/h3><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" ><p><span style=\"color: #666666;\"><span lang=\"EN\" style=\"font-family: Times New Roman;\"> <span style=\"font-size: small;\">A 24-hr run of protonated acetonitrile in a conventional flow system (1\u00a0mL\/min) is approximately $16\/day, with \u00be of a liter consumed, plus the additional amounts required for cleaning and rinsing conventional-scale plumbing.\u00a0 Similar numbers apply for tube-based approaches, where typically a liquid handler is employed up-stream for automated loading of the tubes with sample.\u00a0 A 24-hr run of higher quality, deuterated acetonitrile in a capillary flow system (5\u00a0<\/span><\/span><span lang=\"EN\" style=\"font-family: Symbol;\"><span style=\"font-size: small;\">m<\/span><\/span><span lang=\"EN\" style=\"font-family: Times New Roman;\"><span style=\"font-size: small;\">L\/min) is approximately $10\/day, with less than 5\u00a0mL consumed.\u00a0 Cleaning and rinsing steps require proportionally less than conventional scale as well.\u00a0 The order-of-magnitude difference in solvent utilization is equally true on the back-end of the process as well, where disposal procedures and disposal costs must be accommodated.\u00a0 The purposeful choice of a system that uses ten-fold less solvent yields economic advantage to help you run your lab more efficiently, to invest your resources where they are most needed, and to maintain a responsible position with regard to the disposal of biohazardous materials -advantages of the microflow approach that go beyond mere economics.<\/span><\/span><\/span><\/p>\n<\/div><\/section><\/div><\/div><\/div><\/div>\n<div class=\"flex_column av_one_third  flex_column_div   \" ><p><div class='avia-builder-widget-area clearfix '><div id=\"sg_jquery_scroller_widget-2\" class=\"widget clearfix sg_jquery_scroller_widget_plugin_class\"><h3 class=\"widgettitle\">MICROFLOW NMR FEATURES<\/h3><style type=\"text\/css\">\r\n   \t\/* CSS for the scrollers *\/\r\n\t.vertical_scroller14 {\r\n        position: relative;\r\n        display: block;\r\n        overflow: hidden;\r\n        float: left;\r\n        width: 100%;  \/* 100%; *\/\r\n        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               <a href=\"http:\/\/protasis.net\/blog2014\/?p=2174\">Introducing Encompass<\/a>\r\n                        <\/p>\r\n                                                                                    <p class=\"sgjvs_widget_content\">\r\n                            <h1 style=\"text-align: center;\">Need More Results?<\/h1>\r\n<h5 style=\"text-align: center;\"><b><i>Get <\/i><\/b><b><i>Encompass<\/i><\/b><b><i>. the enterprise scheduler for laboratory samples!<\/i><\/b><\/h5>\r\n<h2 style=\"text-align: center;\"><span style=\"color: #008000;\"><em><strong>Submit. Acquire. Present.<\/strong><\/em><\/span><\/h2>\r\n&nbsp;\r\n<p style=\"text-align: center;\"><\/p>                        <\/p>\r\n                                    <\/li>\r\n                                <li>\r\n                                            <p class=\"sgjvs_widget_title\">\r\n                            <a href=\"http:\/\/protasis.net\/blog2014\/?p=2151\">GRID TEST<\/a>\r\n                        <\/p>\r\n                                                                                    <p class=\"sgjvs_widget_content\">\r\n                            <strong>GRID TEST<\/strong>\r\n\r\n<b><\/b>\r\n\r\n&nbsp;\r\n\r\n&nbsp;\r\n\r\n&nbsp;                        <\/p>\r\n                                    <\/li>\r\n                                <li>\r\n                                            <p class=\"sgjvs_widget_title\">\r\n                            <a href=\"http:\/\/protasis.net\/blog2014\/?p=1993\">One-Minute NMR Platform<\/a>\r\n                        <\/p>\r\n                                                                                    <p class=\"sgjvs_widget_content\">\r\n                            <div class=\"tabcontainer  top_tab  \">\n\r\n\r\n<section class=\"av_tab_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" >    <div data-fake-id=\"#tab-id-1\" class=\"tab active_tab\"  itemprop=\"headline\" >Overview<\/div>\n    <div id=\"tab-id-1-container\" class=\"tab_content active_tab_content\">\n        <div class=\"tab_inner_content invers-color\"  itemprop=\"text\" >\n<h3><\/h3>\n<h3>One-Minute NMR Overview<\/h3>\n<p>Now you can obtain the highest quality NMR spectra automatically with less sample in less time:<\/p>\n<ul>\n<li><a href=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/07\/LEAP-Tower-Side-2-HQ.jpg\"><img class=\"alignright wp-image-2007 size-medium\" src=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/07\/LEAP-Tower-Side-2-HQ-300x225.jpg\" alt=\"LEAP &amp; Tower Side 2 HQ\" width=\"300\" height=\"225\" \/><\/a>Highest mass sensitivity (micrograms)<\/li>\n<li>One minute fluidic cycle time<\/li>\n<li>One minute proton spectra<\/li>\n<li>2D spectra in a few hours<\/li>\n<li>One-Minute NMR Software<\/li>\n<li>Web-based with the same browser interface for Agilent, Bruker, Varian INOVA and JEOL<\/li>\n<li>Load from standard laboratory consumables;\n<ul>\n<li>low volume vials<\/li>\n<li>96-well plates<\/li>\n<li>384-well plates, etc.<\/li>\n<\/ul>\n<\/li>\n<li>Downsize to MicroFlow NMR and save on sample utilization, reagent cost, tube cost and magnet time<\/li>\n<\/ul>\n<h3>Who uses NMR Automation?<\/h3>\n<ul>\n<li>Mass-limited researchers building full libraries of 1D and 2D spectra<\/li>\n<li>Multi-user facilities that want improved NMR productivity<\/li>\n<li>Biofluids analysts need higher throughout for serum and urine<\/li>\n<li>Facility managers wanting to breathe new life into existing 400 MHz NMR systems<\/li>\n<li>Anyone that wants automated use standard microplates or vials<\/li>\n<\/ul>\n<p style=\"color: #000000;\"><b><span style=\"font-family: Arial; font-size: small;\"><i>We believe that end-user collaboration is key to creation of quality products that deliver the results you need.<\/i><\/span><span style=\"color: #666666; font-family: Arial; font-size: small;\">\u00a0<\/span><\/b><\/p>\n<p style=\"color: #000000; text-align: left;\" align=\"right\"><span style=\"color: #666666;\">The One-Minute NMR system was designed by a team of NMR spectroscopists, software developers and fluidic engineers.\u00a0 Participating NMR users helped out by specifying their needs and providing feedback as development began. The resulting modular, expandable Discovery Platform can keep up with your\u00a0 sample demand today and can evolve to meet your laboratory\u2019s changing needs and increasing workloads.\u00a0 One-Minute NMR delivers advanced features across the discovery and development value chain, from natural product chemists to biofluids analysis to trace impurity identification.\u00a0 Every chemist and their managers will appreciate the productivity boost and convenience of walk-away, unattended operation, with special support for overnight samples.\u00a0 When you consider the reduced sample prep for new samples, reduced sample utilization from existing libraries, reduced reagent and solvent consumption, elimination of the cost and\u00a0climbing\u00a0of tubes. and improved magnet utilization due to faster spectral acquisition, this is a system that easily justifies itself in any NMR facility with multiple users or many samples.<\/span><\/p>\n<p style=\"color: #000000; text-align: left;\" align=\"right\"><span style=\"color: #666666;\">Protasis Discovery Platforms deliver amplified performance in software and hardware, applied to real-world customers and samples.<\/span><\/p>\n\n        <\/div>\n    <\/div>\n<\/section>\n\r\n<section class=\"av_tab_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" >    <div data-fake-id=\"#tab-id-2\" class=\"tab \"  itemprop=\"headline\" >Requirements<\/div>\n    <div id=\"tab-id-2-container\" class=\"tab_content \">\n        <div class=\"tab_inner_content invers-color\"  itemprop=\"text\" >\n<h3>One-Minute NMR Requirements<\/h3>\n<p><strong>Operating System<\/strong><\/p>\n<p>Windows XP Professional (Legacy Support for Existing Customers)<\/p>\n<p>Windows 7, 8 or 8.1<\/p>\n<p><strong>RAM<\/strong><\/p>\n<p>4GB (minimum)<\/p>\n<p><strong>Hard Drive<\/strong><\/p>\n<p>1TB (typical installation)<\/p>\n<p><strong>Notes<\/strong><\/p>\n<p>Windows Professional is required. .NET Framework and SQ Server run-time are used.<\/p>\n<p><strong>Compatible NMR Operating Systems<\/strong><\/p>\n<p>Linux<\/p>\n<p>Windows (Bruker)<\/p>\n<p><strong>Compatible Spectrometers<\/strong><\/p>\n<p>Agilent<\/p>\n<p>Varian<\/p>\n<p>Bruker<\/p>\n<p>JEOL<\/p>\n<p><strong>Other<\/strong><\/p>\n<p>Internet Explorer 8 should be used for Windows XP systems.<\/p>\n<p>Internet access is required for the installation.<\/p>\n\n        <\/div>\n    <\/div>\n<\/section>\n\r\n<\/div>\n                        <\/p>\r\n                                    <\/li>\r\n                                <li>\r\n                                            <p class=\"sgjvs_widget_title\">\r\n                            <a href=\"http:\/\/protasis.net\/blog2014\/?p=1951\">Medicinal Chemistry Link<\/a>\r\n                        <\/p>\r\n                                                                                    <p class=\"sgjvs_widget_content\">\r\n                            <a href=\"http:\/\/www.protasis.net\/catalog\/index.php?route=product\/category&amp;path=25_28\">Medicinal Chemistry Page<\/a>\r\n\r\n&nbsp;\r\n\r\n&nbsp;                        <\/p>\r\n                                    <\/li>\r\n                                <li>\r\n                                            <p class=\"sgjvs_widget_title\">\r\n                            <a href=\"http:\/\/protasis.net\/blog2014\/?p=1280\">MicroFlow NMR Features List<\/a>\r\n                        <\/p>\r\n                                                                                    <p class=\"sgjvs_widget_content\">\r\n                            <h2>Features List<\/h2>\r\n&nbsp;\r\n\r\nAdvanced features make MicroFlow NMR a\r\nsuperior alternative in many applications\r\nto both conventional and cryo-cooled NMR probes.\r\n\r\nCapNMR probes provide outstanding value\r\nthat will give you exceptional results and\r\npay for itself in a few months of normal use.\r\n\r\nYou can investigate further on our feature tour.\r\n\r\n&nbsp;\r\n\r\n<span class='mb-center maxbutton-1-center'><span class='maxbutton-1-container mb-container'><a class=\"maxbutton-1 maxbutton maxbutton-catalog-page\" target=\"_blank\" href=\"http:\/\/www.protasis.net\/catalog\/index.php?route=product\/category&path=25_28\"><span class='mb-text'>MedChem<\/span><\/a><\/span><\/span>\r\n\r\n&nbsp;\r\n<h4>Performance, High Sensitivity<\/h4>\r\n&nbsp;\r\n\r\nGet Spectra From A few Micrograms of Sample\r\n\r\nLow Power Allows Broadband Spectra\r\n\r\nHigh Resolution\r\n\r\nHigh Fill Factor and High Observe Factor\r\n\r\nLow Noise \/ Clean Baselines\r\n\r\nHigh Signal-to-Solvent Ratio\r\n\r\nExcellent Salt Tolerance\r\n\r\nRapid Recovery from Steep Solvent Gradients\r\n\r\nHigh Magnetic Field Gradients\r\n\r\nExcellent Multi-Nuclear Sensitivity\r\n\r\nExcellent Thermal Stability\r\n\r\nEfficient Sample Delivery and Recovery\r\n\r\n&nbsp;\r\n<h3>Simple and Effective<\/h3>\r\n&nbsp;\r\n\r\nSensible Sensitivity\r\n\r\nEasy Shimming\r\n\r\nEasy Tuning\r\n\r\nUse All Your Standard NMR Methods\r\n\r\nSample Management Made Simple\r\n\r\nCompatible with Varian, Bruker and JEOL\r\n\r\nEasy Sample Recovery\r\n\r\nSimple, Smooth Flowpath\r\n\r\nCompatible w\/ 300 MHz - 800 MHz Field Strengths\r\n\r\nExcellent Solvent Compatibility\r\n\r\n&nbsp;\r\n<h3>A Technology Boost That Pays for Itself<\/h3>\r\n&nbsp;\r\n\r\nMore Information, Less Sample\r\n\r\nConsume Less Solvent\r\n\r\nAffordable High Sensitivity\r\n\r\nMaximize Magnet Utilization\r\n\r\nEliminate Tube Costs\r\n\r\nUse Deuterated Solvents Exclusively\r\n\r\nLower Disposal Costs\r\n\r\n&nbsp;\r\n<h3>Get the Spectra Now--Get Published Faster<\/h3>\r\n&nbsp;\r\n\r\nWalk-up NMR\r\n\r\nRapid Probe Re-Installation\r\n\r\nFast Shimming with Presets\r\n\r\nFast Syringe Injection\r\n\r\nRapid Sample Loading up to 5 Meters Away\r\n\r\nUp to 100x Faster than a Conventional 5mm Probe\r\n\r\nReduce Time to Acquire Full Set of 1D &amp; 2D Spectra\r\n\r\nNo Waiting for Sample Recovery\r\n\r\nRapid Rinsing for Undetectable Carryover\r\n\r\nRapid Probe Removal and Storage\r\n\r\n&nbsp;\r\n<h3>Flow-Through Reliability<\/h3>\r\n&nbsp;\r\n\r\nFlexible, Precise Injections\r\n\r\nReplaceable Filters Protect Flowpath\r\n\r\nBackpressure Monitoring\r\n\r\n&nbsp;\r\n<h3>Comprehensive Support<\/h3>\r\n&nbsp;\r\n\r\n<strong>Initial<\/strong>\r\nOn-Site Installation\r\nOn-Site Training\r\nDetailed Documentation\r\n90-Day Free Telephone Support\r\n\r\n<strong>Ongoing<\/strong>\r\nOnline Help Desk\r\nFREE Technical Support by Email\r\nPremium Telephone Support\r\nWeb-Based Training\r\nper Incident Repairs OR Umbrella Coverage\r\nSoftware Updates\r\nConsumables Kit\r\n\r\nYour answer to Affordable High Sensitivity. MicroFlow NMR                        <\/p>\r\n                                    <\/li>\r\n                                            <\/ul>\r\n        <\/div> <!-- end of scrolling text -->\r\n    <\/div>  <!-- end of Vertical Scroller -->\r\n\t\t\t<br \/>\r\n\t\t<div style=\"min-height: 20px; vertical-align: bottom; text-align: center;\">\r\n\t\t\t<br \/>\r\n\t\t\t\t\t\t<a href=\"\">read more...<\/a>\r\n\t\t<\/div>\r\n\r\n\t<\/div> <!-- end of Grid Container -->\r\n<\/div><\/div><br \/>\n<\/p><\/div>\n<div class=\"flex_column av_three_fourth  flex_column_div first  \" ><div  class='av_promobox avia-button-yes '>\t\t<div class='avia-promocontent'><\/p>\n<h3>Get Published Faster with CapNMR Probes!<\/h3>\n<p><strong>Collect less. Make less. Save time and money!<\/strong><\/p>\n<\/div><div class='avia-button-wrap avia-button-right '><a href='' class='avia-button  avia-icon_select-no avia-color-theme-color avia-size-large avia-position-right '  target=\"_blank\"   ><span class='avia_iconbox_title' >Learn More<\/span><\/a><\/div>\t<\/div><\/div><div class=\"flex_column av_one_fourth  flex_column_div   \" ><section class=\"av_textblock_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock '   itemprop=\"text\" ><h3>More Information<\/h3>\n<p><strong>MicroFlow NMR Downloads<\/strong><\/p>\n<div class='w3eden'>\n                 <div class=\"navbar navbar-default\" role=\"navigation\">\n  <div class=\"container-fluid\">\n    <!-- Brand and toggle get grouped for better mobile display -->\n    <div class=\"navbar-header\">\n      <button type=\"button\" class=\"navbar-toggle\" data-toggle=\"collapse\" data-target=\"#bs-example-navbar-collapse-1\">\n        <span class=\"sr-only\">Toggle navigation<\/span>\n        <span class=\"icon-bar\"><\/span>\n        <span class=\"icon-bar\"><\/span>\n        <span class=\"icon-bar\"><\/span>\n      <\/button>\n      <a class=\"navbar-brand\" href=\"#\"><\/a>\n    <\/div>\n\n    <!-- Collect the nav links, forms, and other content for toggling -->\n    <div class=\"collapse navbar-collapse\" id=\"bs-example-navbar-collapse-1\">\n\n      <ul class=\"nav navbar-nav navbar-right\">\n       <li class=\"dropdown\">\n                        <a href=\"#\" class=\"dropdown-toggle\" data-toggle=\"dropdown\">Order By  Publish Date <b class=\"caret\"><\/b><\/a>\n                        <ul class=\"dropdown-menu\">\n                         <li><a href=\"http:\/\/protasis.net\/blog2014\/?page_id=424&orderby=title&order=asc\">Title<\/a><\/li>\n                         <!-- li><a href=\"http:\/\/protasis.net\/blog2014\/?page_id=424&orderby=download_count&order=desc\">Downloads<\/a><\/li -->\n                         <li><a href=\"http:\/\/protasis.net\/blog2014\/?page_id=424&orderby=publish_date&order=desc\">Publish Date<\/a><\/li>\n                        <\/ul>\n                     <\/li>\n                     <li class=\"dropdown\">\n                        <a href=\"#\" class=\"dropdown-toggle\" data-toggle=\"dropdown\">Desc <b class=\"caret\"><\/b><\/a>\n                        <ul class=\"dropdown-menu\">\n                         <li><a href=\"http:\/\/protasis.net\/blog2014\/?page_id=424&orderby=create_date&order=asc\">Asc<\/a><\/li>\n                         <li><a href=\"http:\/\/protasis.net\/blog2014\/?page_id=424&orderby=create_date&order=desc\">Desc<\/a><\/li>\n                        <\/ul>\n                     <\/li>\n      <\/ul>\n    <\/div><!-- \/.navbar-collapse -->\n  <\/div><!-- \/.container-fluid -->\n<\/div><div class='row'><\/div><div style='clear:both'><\/div><div class='text-center'><ul  class=\"pagination pagination-centered\"><\/ul><\/div>\n<div style='clear:both'><\/div><div style='clear:both'><\/div><\/div>\n<\/div><\/section><\/div><\/div><\/div><\/div><!-- close content main div --><\/div><\/div><div id='av_section_1' class='avia-section alternate_color avia-section-default avia-no-shadow avia-bg-style-scroll  container_wrap sidebar_right'   ><div class='container' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-424'><div class='entry-content-wrapper clearfix'><\/div><\/div><\/div><!-- close content main div --><\/div><\/div><div id='after_section_1' class='main_color av_default_container_wrap container_wrap sidebar_right'   ><div class='container' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-424'><div class='entry-content-wrapper clearfix'><\/p>\n<div  class='hr hr-default '><span class='hr-inner ' ><span class='hr-inner-style'><\/span><\/span><\/div>\n<div class=\"flex_column av_two_third  flex_column_div first  \" ><section class=\"av_textblock_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock '   itemprop=\"text\" ><h3>Featured Speaker<\/h3>\n<p><strong>Dave Detlefsen, Novatia LLC<br \/>\n<\/strong><\/p>\n<p>Hear about a contract lab&#8217;s experiences with micrcoil NMR probes.\u00a0 Doing more with less!<\/p>\n<\/div><\/section><br \/>\n<div  class='avia-video avia-video-4-3  '  itemprop=\"video\" itemtype=\"https:\/\/schema.org\/VideoObject\" ><div class='avia-iframe-wrap'><iframe width=\"1333\" height=\"1000\" src=\"https:\/\/www.youtube.com\/embed\/IfPjPfIUcBY?feature=oembed\" frameborder=\"0\" allowfullscreen><\/iframe><\/div><\/div><\/p><\/div>\n<div class=\"flex_column av_one_third  flex_column_div   \" ><section class=\"av_textblock_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock '   itemprop=\"text\" ><h3 style=\"text-align: center;\">Reference Customer<\/h3>\n<p style=\"text-align: center;\"><strong>Novatia LLC<br \/>\n<\/strong><\/p>\n<\/div><\/section><br \/>\n<div  data-autoplay='true'  data-interval='10'  data-animation='slide'  class='avia-logo-element-container av-border-deactivate avia-logo-slider avia-content-slider avia-smallarrow-slider avia-content-slider-active noHover avia-content-slider1 avia-content-slider-odd ' ><div class='avia-smallarrow-slider-heading  no-logo-slider-navigation '><div class='new-special-heading'><h3>Walk-Up Open-Access NMR<\/h3><\/div><\/div><div class='avia-content-slider-inner'><div class='slide-entry-wrap'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div data-avia-tooltip=\"Novatia Logo\" class='slide-entry flex_column no_margin post-entry slide-entry-overview slide-loop-1 slide-parity-odd  post-entry-last  av_fullwidth first real-thumbnail'><img  itemprop=\"contentURL\"  width=\"157\" height=\"57\" src=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/Novatia_Old_Logo_Long.jpg\" class=\"attachment-no scaling size-no scaling\" alt=\"\" decoding=\"async\" loading=\"lazy\" \/><\/div><\/div><\/div><\/div><br \/>\n<section class=\"av_textblock_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock '   itemprop=\"text\" ><p style=\"padding: 0px; margin: 1em 0px; line-height: 1.75em; color: #333333; font-family: 'Varela Round', 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 11px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px; background-color: #ffffff;\">Novatia is the only contract NMR laboratory that offers high sensitivity (microgram to nanogram scale) NMR contract analysis specifically designed for:<\/p>\n<ul style=\"padding: 0px; margin: 1em 0px; color: #333333; font-family: 'Varela Round', 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 11px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px; background-color: #ffffff;\">\n<li style=\"padding: 0px; margin: 0.5em 0px 0.5em 2em; list-style-type: square;\">natural product and other isolation chemists<\/li>\n<li style=\"padding: 0px; margin: 0.5em 0px 0.5em 2em; list-style-type: square;\">synthetic chemists (especially where synthesis is multistep and low yield)<\/li>\n<li style=\"padding: 0px; margin: 0.5em 0px 0.5em 2em; list-style-type: square;\">chemists &amp; biologists with limited sample supply<\/li>\n<\/ul>\n<p><strong>\u00a0<\/strong><\/p>\n<\/div><\/section><\/p><\/div>\n<\/div><\/div><\/div><!-- close content main div --><\/div><\/div><div id='av_section_2' class='avia-section alternate_color avia-section-default avia-no-shadow avia-bg-style-scroll  container_wrap sidebar_right'   ><div class='container' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-424'><div class='entry-content-wrapper clearfix'>\n<section class=\"av_textblock_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock '   itemprop=\"text\" ><h3 style=\"text-align: left;\">MicroFlow NMR Blog Articles<\/h3>\n<\/div><\/section>\n<\/div><\/div><\/div><!-- close content main div --><\/div><\/div><div id='after_section_2' class='main_color av_default_container_wrap container_wrap sidebar_right'   ><div class='container' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-424'><div class='entry-content-wrapper clearfix'>\n<div class=\"flex_column av_three_fourth  flex_column_div first  \" ><div class='template-blog '  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/Blog\" ><article class='post-entry post-entry-type-image post-entry-1280 post-loop-1 post-parity-odd multi-big  post-1280 post type-post status-publish format-image has-post-thumbnail hentry category-flowthru-capnmr category-microflow-nmr category-natural-products post_format-post-format-image'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" ><div class=\"big-preview multi-big\"><div class=\"avia-post-format-image\"><a href=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500.jpg\"><img width=\"500\" height=\"500\" src=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500.jpg\" class=\"attachment-large size-large wp-post-image\" alt=\"\" decoding=\"async\" loading=\"lazy\" srcset=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500.jpg 500w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500-80x80.jpg 80w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500-300x300.jpg 300w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500-36x36.jpg 36w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500-180x180.jpg 180w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500-120x120.jpg 120w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500-450x450.jpg 450w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/a><\/div><\/div><div class='blog-meta'><a href='http:\/\/protasis.net\/blog2014\/?post_format=image' class='post-author-format-type'><span class='rounded-container'><span class=\"iconfont\" aria-hidden='true' data-av_icon='\ue80f' data-av_iconfont='entypo-fontello'><\/span><\/span><\/a><\/div><div class='entry-content-wrapper clearfix image-content'><header class=\"entry-content-header\"><h2 class='post-title entry-title'  itemprop=\"headline\" >\t<a href='http:\/\/protasis.net\/blog2014\/?p=1280' rel='bookmark' title='Permanent Link: MicroFlow NMR Features List'>MicroFlow NMR Features List\t\t\t<span class='post-format-icon minor-meta'><\/span>\t<\/a><\/h2><span class='post-meta-infos'><time class='date-container minor-meta updated' >June 12, 2014<\/time><span class='text-sep text-sep-date'>\/<\/span><span class='comment-container minor-meta'><a href=\"http:\/\/protasis.net\/blog2014\/?p=1280#respond\" class=\"comments-link\" >0 Comments<\/a><\/span><span class='text-sep text-sep-comment'>\/<\/span><span class=\"blog-categories minor-meta\">in <a href=\"http:\/\/protasis.net\/blog2014\/?cat=38\" rel=\"tag\">FlowThru CapNMR<\/a>, <a href=\"http:\/\/protasis.net\/blog2014\/?cat=28\" rel=\"tag\">MicroFlow NMR<\/a>, <a href=\"http:\/\/protasis.net\/blog2014\/?cat=8\" rel=\"tag\">Natural Products<\/a> <\/span><span class=\"text-sep text-sep-cat\">\/<\/span><span class=\"blog-author minor-meta\">by <span class=\"entry-author-link\" ><span class=\"vcard author\"><span class=\"fn\"><a href=\"http:\/\/protasis.net\/blog2014\/?author=2\" title=\"Posts by David Strand\" rel=\"author\">David Strand<\/a><\/span><\/span><\/span><\/span><\/span><\/header><div class=\"entry-content\"  itemprop=\"text\" ><h2>Features List<\/h2>\n<p>&nbsp;<\/p>\n<p>Advanced features make MicroFlow NMR a<br \/>\nsuperior alternative in many applications<br \/>\nto both conventional and cryo-cooled NMR probes.<\/p>\n<p>CapNMR probes provide outstanding value<br \/>\nthat will give you exceptional results and<br \/>\npay for itself in a few months of normal use.<\/p>\n<p>You can investigate further on our feature tour.<\/p>\n<p>&nbsp;<\/p>\n<span class='mb-center maxbutton-1-center'><span class='maxbutton-1-container mb-container'><a class=\"maxbutton-1 maxbutton maxbutton-catalog-page\" target=\"_blank\" href=\"http:\/\/www.protasis.net\/catalog\/index.php?route=product\/category&path=25_28\"><span class='mb-text'>MedChem<\/span><\/a><\/span><\/span>\n<p>&nbsp;<\/p>\n<h4>Performance, High Sensitivity<\/h4>\n<p>&nbsp;<\/p>\n<p>Get Spectra From A few Micrograms of Sample<\/p>\n<p>Low Power Allows Broadband Spectra<\/p>\n<p>High Resolution<\/p>\n<p>High Fill Factor and High Observe Factor<\/p>\n<p>Low Noise \/ Clean Baselines<\/p>\n<p>High Signal-to-Solvent Ratio<\/p>\n<p>Excellent Salt Tolerance<\/p>\n<p>Rapid Recovery from Steep Solvent Gradients<\/p>\n<p>High Magnetic Field Gradients<\/p>\n<p>Excellent Multi-Nuclear Sensitivity<\/p>\n<p>Excellent Thermal Stability<\/p>\n<p>Efficient Sample Delivery and Recovery<\/p>\n<p>&nbsp;<\/p>\n<h3>Simple and Effective<\/h3>\n<p>&nbsp;<\/p>\n<p>Sensible Sensitivity<\/p>\n<p>Easy Shimming<\/p>\n<p>Easy Tuning<\/p>\n<p>Use All Your Standard NMR Methods<\/p>\n<p>Sample Management Made Simple<\/p>\n<p>Compatible with Varian, Bruker and JEOL<\/p>\n<p>Easy Sample Recovery<\/p>\n<p>Simple, Smooth Flowpath<\/p>\n<p>Compatible w\/ 300 MHz &#8211; 800 MHz Field Strengths<\/p>\n<p>Excellent Solvent Compatibility<\/p>\n<p>&nbsp;<\/p>\n<h3>A Technology Boost That Pays for Itself<\/h3>\n<p>&nbsp;<\/p>\n<p>More Information, Less Sample<\/p>\n<p>Consume Less Solvent<\/p>\n<p>Affordable High Sensitivity<\/p>\n<p>Maximize Magnet Utilization<\/p>\n<p>Eliminate Tube Costs<\/p>\n<p>Use Deuterated Solvents Exclusively<\/p>\n<p>Lower Disposal Costs<\/p>\n<p>&nbsp;<\/p>\n<h3>Get the Spectra Now&#8211;Get Published Faster<\/h3>\n<p>&nbsp;<\/p>\n<p>Walk-up NMR<\/p>\n<p>Rapid Probe Re-Installation<\/p>\n<p>Fast Shimming with Presets<\/p>\n<p>Fast Syringe Injection<\/p>\n<p>Rapid Sample Loading up to 5 Meters Away<\/p>\n<p>Up to 100x Faster than a Conventional 5mm Probe<\/p>\n<p>Reduce Time to Acquire Full Set of 1D &amp; 2D Spectra<\/p>\n<p>No Waiting for Sample Recovery<\/p>\n<p>Rapid Rinsing for Undetectable Carryover<\/p>\n<p>Rapid Probe Removal and Storage<\/p>\n<p>&nbsp;<\/p>\n<h3>Flow-Through Reliability<\/h3>\n<p>&nbsp;<\/p>\n<p>Flexible, Precise Injections<\/p>\n<p>Replaceable Filters Protect Flowpath<\/p>\n<p>Backpressure Monitoring<\/p>\n<p>&nbsp;<\/p>\n<h3>Comprehensive Support<\/h3>\n<p>&nbsp;<\/p>\n<p><strong>Initial<\/strong><br \/>\nOn-Site Installation<br \/>\nOn-Site Training<br \/>\nDetailed Documentation<br \/>\n90-Day Free Telephone Support<\/p>\n<p><strong>Ongoing<\/strong><br \/>\nOnline Help Desk<br \/>\nFREE Technical Support by Email<br \/>\nPremium Telephone Support<br \/>\nWeb-Based Training<br \/>\nper Incident Repairs OR Umbrella Coverage<br \/>\nSoftware Updates<br \/>\nConsumables Kit<\/p>\n<p>Your answer to Affordable High Sensitivity. MicroFlow NMR<\/p>\n<\/div><footer class=\"entry-footer\"><\/footer><div class='post_delimiter'><\/div><\/div><div class='post_author_timeline'><\/div><span class='hidden'>\n\t\t\t<span class='av-structured-data'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\"  itemprop='image'>\n\t\t\t\t\t   <span itemprop='url' >http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500.jpg<\/span>\n\t\t\t\t\t   <span itemprop='height' >500<\/span>\n\t\t\t\t\t   <span itemprop='width' >500<\/span>\n\t\t\t\t  <\/span><span class='av-structured-data'  itemprop=\"publisher\" itemtype=\"https:\/\/schema.org\/Organization\" itemscope=\"itemscope\" >\n\t\t\t\t<span itemprop='name'>David Strand<\/span>\n\t\t\t\t<span itemprop='logo' itemscope itemtype='http:\/\/schema.org\/ImageObject'>\n\t\t\t\t   <span itemprop='url'>http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/Protasis-MRM-LOGO2-300x128.png<\/span>\n\t\t\t\t <\/span>\n\t\t\t  <\/span><span class='av-structured-data'  itemprop=\"author\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/Person\" ><span itemprop='name'>David Strand<\/span><\/span><span class='av-structured-data'  itemprop=\"datePublished\" datetime=\"2014-06-12T06:47:35+00:00\" >2014-06-12 06:47:35<\/span><span class='av-structured-data'  itemprop=\"dateModified\" itemtype=\"https:\/\/schema.org\/dateModified\" >2014-07-05 19:45:34<\/span><span class='av-structured-data'  itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/mainEntityOfPage\" ><span itemprop='name'>MicroFlow NMR Features List<\/span><\/span><\/span><\/article><article class='post-entry post-entry-type-standard post-entry-856 post-loop-2 post-parity-even post-entry-last multi-big with-slider post-856 post type-post status-publish format-standard has-post-thumbnail hentry category-microflow-nmr category-notebook tag-capnmr tag-microcoils'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" ><div class=\"big-preview multi-big\"><a href=\"http:\/\/protasis.net\/blog2014\/?p=856\" title=\"White Paper &#8211; Less is More\"><img width=\"495\" height=\"400\" src=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500-495x400.jpg\" class=\"attachment-portfolio size-portfolio wp-post-image\" alt=\"\" decoding=\"async\" loading=\"lazy\" \/><\/a><\/div><div class='blog-meta'><a href='http:\/\/protasis.net\/blog2014\/?author=2' class='post-author-format-type'><span class='rounded-container'><img alt='David Strand' src='http:\/\/1.gravatar.com\/avatar\/7a18a0dbbc7908071017c8100d6e7283?s=81&#038;d=blank&#038;r=g' srcset='http:\/\/1.gravatar.com\/avatar\/7a18a0dbbc7908071017c8100d6e7283?s=162&#038;d=blank&#038;r=g 2x' class='avatar avatar-81 photo' height='81' width='81' loading='lazy' decoding='async'\/><span class=\"iconfont\" aria-hidden='true' data-av_icon='\ue836' data-av_iconfont='entypo-fontello'><\/span><\/span><\/a><\/div><div class='entry-content-wrapper clearfix standard-content'><header class=\"entry-content-header\"><h2 class='post-title entry-title'  itemprop=\"headline\" >\t<a href='http:\/\/protasis.net\/blog2014\/?p=856' rel='bookmark' title='Permanent Link: White Paper &#8211; Less is More'>White Paper &#8211; Less is More\t\t\t<span class='post-format-icon minor-meta'><\/span>\t<\/a><\/h2><span class='post-meta-infos'><time class='date-container minor-meta updated' >May 27, 2014<\/time><span class='text-sep text-sep-date'>\/<\/span><span class='comment-container minor-meta'><a href=\"http:\/\/protasis.net\/blog2014\/?p=856#respond\" class=\"comments-link\" >0 Comments<\/a><\/span><span class='text-sep text-sep-comment'>\/<\/span><span class=\"blog-categories minor-meta\">in <a href=\"http:\/\/protasis.net\/blog2014\/?cat=28\" rel=\"tag\">MicroFlow NMR<\/a>, <a href=\"http:\/\/protasis.net\/blog2014\/?cat=36\" rel=\"tag\">Notebook<\/a> <\/span><span class=\"text-sep text-sep-cat\">\/<\/span><span class=\"blog-author minor-meta\">by <span class=\"entry-author-link\" ><span class=\"vcard author\"><span class=\"fn\"><a href=\"http:\/\/protasis.net\/blog2014\/?author=2\" title=\"Posts by David Strand\" rel=\"author\">David Strand<\/a><\/span><\/span><\/span><\/span><\/span><\/header><div class=\"entry-content\"  itemprop=\"text\" ><p><span style=\"font-size: 14px;\"><a href=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/mathsymbolslessthanbnw-150x150.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"alignleft size-full wp-image-857\" src=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/mathsymbolslessthanbnw-150x150.jpg\" alt=\"mathsymbolslessthanbnw-150x150\" width=\"150\" height=\"150\" srcset=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/mathsymbolslessthanbnw-150x150.jpg 150w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/mathsymbolslessthanbnw-150x150-80x80.jpg 80w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/mathsymbolslessthanbnw-150x150-36x36.jpg 36w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/mathsymbolslessthanbnw-150x150-120x120.jpg 120w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/a>The combination of sensitive capillary NMR probes, fast liquid handlers and advanced heteronuclear methods is allowing NMR to take its place alongside LC-MS in life science research. Using only micrograms of sample, MicroFlow NMR can provide definitive verification of structure and quantitation of sample amount and purity for routine characterization of new or existing molecular libraries.<\/span> Read the white paper to learn about microil <strong><em><span style=\"color: #0000ff;\">sensitivity, simplicity and economy!<\/span><\/em><\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<\/div><footer class=\"entry-footer\"><\/footer><div class='post_delimiter'><\/div><\/div><div class='post_author_timeline'><\/div><span class='hidden'>\n\t\t\t<span class='av-structured-data'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\"  itemprop='image'>\n\t\t\t\t\t   <span itemprop='url' >http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500.jpg<\/span>\n\t\t\t\t\t   <span itemprop='height' >500<\/span>\n\t\t\t\t\t   <span itemprop='width' >500<\/span>\n\t\t\t\t  <\/span><span class='av-structured-data'  itemprop=\"publisher\" itemtype=\"https:\/\/schema.org\/Organization\" itemscope=\"itemscope\" >\n\t\t\t\t<span itemprop='name'>David Strand<\/span>\n\t\t\t\t<span itemprop='logo' itemscope itemtype='http:\/\/schema.org\/ImageObject'>\n\t\t\t\t   <span itemprop='url'>http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/Protasis-MRM-LOGO2-300x128.png<\/span>\n\t\t\t\t <\/span>\n\t\t\t  <\/span><span class='av-structured-data'  itemprop=\"author\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/Person\" ><span itemprop='name'>David Strand<\/span><\/span><span class='av-structured-data'  itemprop=\"datePublished\" datetime=\"2014-05-27T06:34:07+00:00\" >2014-05-27 06:34:07<\/span><span class='av-structured-data'  itemprop=\"dateModified\" itemtype=\"https:\/\/schema.org\/dateModified\" >2014-07-05 19:47:21<\/span><span class='av-structured-data'  itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/mainEntityOfPage\" ><span itemprop='name'>White Paper - Less is More<\/span><\/span><\/span><\/article><div class='multi-big'><\/div><\/div><\/div>\n<div class=\"flex_column av_one_fourth  flex_column_div   \" ><p><div id='av-magazine-1' class='av-magazine   av-magazine-top-bar-active av-magazine-tabs-active' ><div class='av-magazine-top-bar ' ><a href='http:\/\/' class='av-magazine-top-heading'>OAHT-NMR Articles<\/a><div class='av-magazine-sort ' data-magazine-id='1' ><div class='av-sort-by-term'><a href=\"#\" data-filter=\"sort_all\" class=\"all_sort_button active_sort\"><span class=\"inner_sort_button\"><span>All<\/span><\/span><\/a><span class='text-sep microflow-nmr_sort_sep'>\/<\/span><a href=\"#\" data-filter=\"sort_28\" class=\"microflow-nmr_sort_button \" ><span class=\"inner_sort_button\"><span>MicroFlow NMR<\/span><\/span><\/a><span class='text-sep natural-products_sort_sep'>\/<\/span><a href=\"#\" data-filter=\"sort_8\" class=\"natural-products_sort_button \" ><span class=\"inner_sort_button\"><span>Natural Products<\/span><\/span><\/a><\/div><\/div><\/div><div class='av-magazine-group sort_all'><article class='hentry av-magazine-entry av-magazine-entry-id-1280 av-magazine-format-image av-magazine-type-post av-magazine-entry-1 av-magazine-entry-small av-magazine-no-thumb'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='av-magazine-content-wrap'><header class='entry-content-header'><time class='av-magazine-time updated'  itemprop=\"datePublished\" datetime=\"2014-06-12T06:47:35+00:00\" >June 12, 2014<\/time><span class='av-magazine-text-sep text-sep-date'>\/<\/span><span class=\"av-magazine-author minor-meta\">by <span class=\"av-magazine-author-link\"  itemprop=\"author\" ><span class='av-magazine-author meta-color vcard author'><span class='fn'><a href=http:\/\/protasis.net\/blog2014\/?author=2 title=\"by David Strand\" rel=\"author\">David Strand<\/a><\/span><\/span><\/span><\/span><h3 class='av-magazine-title entry-title'  itemprop=\"headline\" ><a href='http:\/\/protasis.net\/blog2014\/?p=1280' title='Link to: MicroFlow NMR Features List'>MicroFlow NMR Features List<\/a><\/h3><\/header><\/div><footer class='entry-footer'><\/footer><\/article><article class='hentry av-magazine-entry av-magazine-entry-id-856 av-magazine-format-standard av-magazine-type-post av-magazine-entry-2 av-magazine-entry-small av-magazine-no-thumb'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='av-magazine-content-wrap'><header class='entry-content-header'><time class='av-magazine-time updated'  itemprop=\"datePublished\" datetime=\"2014-05-27T06:34:07+00:00\" >May 27, 2014<\/time><span class='av-magazine-text-sep text-sep-date'>\/<\/span><span class=\"av-magazine-author minor-meta\">by <span class=\"av-magazine-author-link\"  itemprop=\"author\" ><span class='av-magazine-author meta-color vcard author'><span class='fn'><a href=http:\/\/protasis.net\/blog2014\/?author=2 title=\"by David Strand\" rel=\"author\">David Strand<\/a><\/span><\/span><\/span><\/span><h3 class='av-magazine-title entry-title'  itemprop=\"headline\" ><a href='http:\/\/protasis.net\/blog2014\/?p=856' title='Link to: White Paper &#8211; Less is More'>White Paper &#8211; Less is More<\/a><\/h3><\/header><\/div><footer class='entry-footer'><\/footer><\/article><\/div><div class='av-magazine-group av-hidden-mag sort_28'><article class='hentry av-magazine-entry av-magazine-entry-id-1280 av-magazine-format-image av-magazine-type-post av-magazine-entry-1 av-magazine-entry-small av-magazine-no-thumb'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='av-magazine-content-wrap'><header class='entry-content-header'><time class='av-magazine-time updated'  itemprop=\"datePublished\" datetime=\"2014-06-12T06:47:35+00:00\" >June 12, 2014<\/time><span class='av-magazine-text-sep text-sep-date'>\/<\/span><span class=\"av-magazine-author minor-meta\">by <span class=\"av-magazine-author-link\"  itemprop=\"author\" ><span class='av-magazine-author meta-color vcard author'><span class='fn'><a href=http:\/\/protasis.net\/blog2014\/?author=2 title=\"by David Strand\" rel=\"author\">David Strand<\/a><\/span><\/span><\/span><\/span><h3 class='av-magazine-title entry-title'  itemprop=\"headline\" ><a href='http:\/\/protasis.net\/blog2014\/?p=1280' title='Link to: MicroFlow NMR Features List'>MicroFlow NMR Features List<\/a><\/h3><\/header><\/div><footer class='entry-footer'><\/footer><\/article><article class='hentry av-magazine-entry av-magazine-entry-id-856 av-magazine-format-standard av-magazine-type-post av-magazine-entry-2 av-magazine-entry-small av-magazine-no-thumb'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='av-magazine-content-wrap'><header class='entry-content-header'><time class='av-magazine-time updated'  itemprop=\"datePublished\" datetime=\"2014-05-27T06:34:07+00:00\" >May 27, 2014<\/time><span class='av-magazine-text-sep text-sep-date'>\/<\/span><span class=\"av-magazine-author minor-meta\">by <span class=\"av-magazine-author-link\"  itemprop=\"author\" ><span class='av-magazine-author meta-color vcard author'><span class='fn'><a href=http:\/\/protasis.net\/blog2014\/?author=2 title=\"by David Strand\" rel=\"author\">David Strand<\/a><\/span><\/span><\/span><\/span><h3 class='av-magazine-title entry-title'  itemprop=\"headline\" ><a href='http:\/\/protasis.net\/blog2014\/?p=856' title='Link to: White Paper &#8211; Less is More'>White Paper &#8211; Less is More<\/a><\/h3><\/header><\/div><footer class='entry-footer'><\/footer><\/article><\/div><div class='av-magazine-group av-hidden-mag sort_8'><article class='hentry av-magazine-entry av-magazine-entry-id-1280 av-magazine-format-image av-magazine-type-post av-magazine-entry-1 av-magazine-entry-small av-magazine-no-thumb'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='av-magazine-content-wrap'><header class='entry-content-header'><time class='av-magazine-time updated'  itemprop=\"datePublished\" datetime=\"2014-06-12T06:47:35+00:00\" >June 12, 2014<\/time><span class='av-magazine-text-sep text-sep-date'>\/<\/span><span class=\"av-magazine-author minor-meta\">by <span class=\"av-magazine-author-link\"  itemprop=\"author\" ><span class='av-magazine-author meta-color vcard author'><span class='fn'><a href=http:\/\/protasis.net\/blog2014\/?author=2 title=\"by David Strand\" rel=\"author\">David Strand<\/a><\/span><\/span><\/span><\/span><h3 class='av-magazine-title entry-title'  itemprop=\"headline\" ><a href='http:\/\/protasis.net\/blog2014\/?p=1280' title='Link to: MicroFlow NMR Features List'>MicroFlow NMR Features List<\/a><\/h3><\/header><\/div><footer class='entry-footer'><\/footer><\/article><\/div><\/div><br \/>\n<div  data-autoplay='1'  data-interval='15'  data-animation='fade'  data-show_slide_delay='90'  class='avia-content-slider avia-content-slider-active avia-content-slider1 avia-content-slider-odd '  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/Blog\" ><div class='avia-content-slider-inner'><div class='slide-entry-wrap'><article class='slide-entry flex_column  post-entry post-entry-1280 slide-entry-overview slide-loop-1 slide-parity-odd  av_fullwidth first real-thumbnail'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><a href='http:\/\/protasis.net\/blog2014\/?p=1280' data-rel='slide-1' class='slide-image' title=''><img width=\"495\" height=\"400\" src=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500-495x400.jpg\" class=\"attachment-portfolio size-portfolio wp-post-image\" alt=\"\" decoding=\"async\" loading=\"lazy\" \/><\/a><div class='slide-content'><header class=\"entry-content-header\"><span class=\"blog-categories minor-meta\"><a href=\"http:\/\/protasis.net\/blog2014\/?cat=38\" rel=\"tag\">FlowThru CapNMR<\/a>, <a href=\"http:\/\/protasis.net\/blog2014\/?cat=28\" rel=\"tag\">MicroFlow NMR<\/a>, <a href=\"http:\/\/protasis.net\/blog2014\/?cat=8\" rel=\"tag\">Natural Products<\/a> <\/span><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" ><a href='http:\/\/protasis.net\/blog2014\/?p=1280' title='MicroFlow NMR Features List'>MicroFlow NMR Features List<\/a><\/h3><span class=\"av-vertical-delimiter\"><\/span><\/header><div class='slide-meta'><div class='slide-meta-comments'><a href='http:\/\/protasis.net\/blog2014\/?p=1280#respond'>0 Comments<\/a><\/div><div class='slide-meta-del'>\/<\/div><time class='slide-meta-time updated'  itemprop=\"datePublished\" datetime=\"2014-06-12T06:47:35+00:00\" >June 12, 2014<\/time><\/div><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" >Features List\r\n&nbsp;\r\n\r\nAdvanced features make MicroFlow NMR\u2026<div class=\"read-more-link\"><a href=\"http:\/\/protasis.net\/blog2014\/?p=1280\" class=\"more-link\">Read more<span class=\"more-link-arrow\">  &rarr;<\/span><\/a><\/div><\/div><\/div><footer class=\"entry-footer\"><\/footer><span class='hidden'>\n\t\t\t<span class='av-structured-data'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\"  itemprop='image'>\n\t\t\t\t\t   <span itemprop='url' >http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500.jpg<\/span>\n\t\t\t\t\t   <span itemprop='height' >500<\/span>\n\t\t\t\t\t   <span itemprop='width' >500<\/span>\n\t\t\t\t  <\/span><span class='av-structured-data'  itemprop=\"publisher\" itemtype=\"https:\/\/schema.org\/Organization\" itemscope=\"itemscope\" >\n\t\t\t\t<span itemprop='name'>David Strand<\/span>\n\t\t\t\t<span itemprop='logo' itemscope itemtype='http:\/\/schema.org\/ImageObject'>\n\t\t\t\t   <span itemprop='url'>http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/Protasis-MRM-LOGO2-300x128.png<\/span>\n\t\t\t\t <\/span>\n\t\t\t  <\/span><span class='av-structured-data'  itemprop=\"author\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/Person\" ><span itemprop='name'>David Strand<\/span><\/span><span class='av-structured-data'  itemprop=\"datePublished\" datetime=\"2014-05-27T06:34:07+00:00\" >2014-06-12 06:47:35<\/span><span class='av-structured-data'  itemprop=\"dateModified\" itemtype=\"https:\/\/schema.org\/dateModified\" >2014-07-05 19:45:34<\/span><span class='av-structured-data'  itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/mainEntityOfPage\" ><span itemprop='name'>MicroFlow NMR Features List<\/span><\/span><\/span><\/article><\/div><div class='slide-entry-wrap'><article class='slide-entry flex_column  post-entry post-entry-856 slide-entry-overview slide-loop-2 slide-parity-odd  post-entry-last  av_fullwidth first real-thumbnail'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><a href='http:\/\/protasis.net\/blog2014\/?p=856' data-rel='slide-1' class='slide-image' title=''><img width=\"495\" height=\"400\" src=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500-495x400.jpg\" class=\"attachment-portfolio size-portfolio wp-post-image\" alt=\"\" decoding=\"async\" loading=\"lazy\" \/><\/a><div class='slide-content'><header class=\"entry-content-header\"><span class=\"blog-categories minor-meta\"><a href=\"http:\/\/protasis.net\/blog2014\/?cat=28\" rel=\"tag\">MicroFlow NMR<\/a>, <a href=\"http:\/\/protasis.net\/blog2014\/?cat=36\" rel=\"tag\">Notebook<\/a> <\/span><h3 class='slide-entry-title entry-title'  itemprop=\"headline\" ><a href='http:\/\/protasis.net\/blog2014\/?p=856' title='White Paper - Less is More'>White Paper - Less is More<\/a><\/h3><span class=\"av-vertical-delimiter\"><\/span><\/header><div class='slide-meta'><div class='slide-meta-comments'><a href='http:\/\/protasis.net\/blog2014\/?p=856#respond'>0 Comments<\/a><\/div><div class='slide-meta-del'>\/<\/div><time class='slide-meta-time updated'  itemprop=\"datePublished\" datetime=\"2014-05-27T06:34:07+00:00\" >May 27, 2014<\/time><\/div><div class='slide-entry-excerpt entry-content'  itemprop=\"text\" >The combination of sensitive capillary NMR probes, fast liquid\u2026<div class=\"read-more-link\"><a href=\"http:\/\/protasis.net\/blog2014\/?p=856\" class=\"more-link\">Read more<span class=\"more-link-arrow\">  &rarr;<\/span><\/a><\/div><\/div><\/div><footer class=\"entry-footer\"><\/footer><span class='hidden'>\n\t\t\t<span class='av-structured-data'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\"  itemprop='image'>\n\t\t\t\t\t   <span itemprop='url' >http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/image006-500x500.jpg<\/span>\n\t\t\t\t\t   <span itemprop='height' >500<\/span>\n\t\t\t\t\t   <span itemprop='width' >500<\/span>\n\t\t\t\t  <\/span><span class='av-structured-data'  itemprop=\"publisher\" itemtype=\"https:\/\/schema.org\/Organization\" itemscope=\"itemscope\" >\n\t\t\t\t<span itemprop='name'>David Strand<\/span>\n\t\t\t\t<span itemprop='logo' itemscope itemtype='http:\/\/schema.org\/ImageObject'>\n\t\t\t\t   <span itemprop='url'>http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/Protasis-MRM-LOGO2-300x128.png<\/span>\n\t\t\t\t <\/span>\n\t\t\t  <\/span><span class='av-structured-data'  itemprop=\"author\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/Person\" ><span itemprop='name'>David Strand<\/span><\/span><span class='av-structured-data'  itemprop=\"datePublished\" datetime=\"2014-05-27T06:34:07+00:00\" >2014-05-27 06:34:07<\/span><span class='av-structured-data'  itemprop=\"dateModified\" itemtype=\"https:\/\/schema.org\/dateModified\" >2014-07-05 19:47:21<\/span><span class='av-structured-data'  itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/mainEntityOfPage\" ><span itemprop='name'>White Paper - Less is More<\/span><\/span><\/span><\/article><\/div><\/div><div class='avia-slideshow-arrows avia-slideshow-controls'><a href='#prev' class='prev-slide' aria-hidden='true' data-av_icon='\ue87c' data-av_iconfont='entypo-fontello'>Previous<\/a><a href='#next' class='next-slide' aria-hidden='true' data-av_icon='\ue87d' 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