{"id":181,"date":"2014-05-11T15:33:19","date_gmt":"2014-05-11T15:33:19","guid":{"rendered":"http:\/\/protasis.net\/blog2014\/?page_id=181"},"modified":"2014-07-04T08:23:21","modified_gmt":"2014-07-04T08:23:21","slug":"grid","status":"publish","type":"page","link":"http:\/\/protasis.net\/blog2014\/?page_id=181","title":{"rendered":"Quotes"},"content":{"rendered":"<div class=\"flex_column av_two_third  flex_column_div first  \" ><section class=\"av_textblock_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock '   itemprop=\"text\" ><h2>Customer Quote<\/h2>\n<\/div><\/section><br \/>\n<div  data-autoplay='1'  data-interval='20'  data-animation='fade'  data-hoverpause='1'  class='avia-testimonial-wrapper avia-slider-testimonials avia-slider-1-testimonials avia_animate_when_almost_visible '>\n<section class ='avia-testimonial-row'><div class='avia-testimonial av_one_full flex_column no_margin avia-testimonial-row-1 avia-first-testimonial'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/Person\" ><div class='avia-testimonial_inner'><div class='avia-testimonial-content '    itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><p style=\"text-align: left;\" align=\"right\"><span style=\"color: #666666;\"> <span style=\"font-size: small;\">\u201cAn analysis of biofluids (blood, urine, cell extracts, etc.) provides a snapshot of the biological processes of an individual that can be used in applications from diagnostics to drug efficacy and toxicity. The Protasis\/MRM capillary NMR automation system is an essential component of Novatia\u2019s biofluid NMR analysis package and allows us to provide a unique service to the research community.\u201d<\/span><\/span><\/p>\n<p style=\"text-align: left;\" align=\"right\"><span style=\"color: #666666;\"> <span style=\"font-family: Tahoma; font-size: small;\"> &#8220;As a contract laboratory with hundreds of samples in backlog, we needed a way to get the most out of our available magnet time. We purchased OneMinuteNMR because it is the best and most cost-effective NMR automation system available.&#8221; <\/span> <\/span><\/p>\n<\/div><div class='avia-testimonial-meta'><div class='avia-testimonial-arrow-wrap'><div class='avia-arrow'><\/div><\/div><div class='avia-testimonial-meta-mini'><strong  class='avia-testimonial-name'    itemprop=\"name\" >Dave Detlefsen<\/strong><span  class='avia-testimonial-subtitle '    itemprop=\"jobTitle\" >Human Serum Application Note, Novatia, LLC<\/span><\/div><\/div><\/div><\/div>\n<div class='avia-testimonial av_one_full flex_column no_margin avia-testimonial-row-1 '  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/Person\" ><div class='avia-testimonial_inner'><div class='avia-testimonial-content '    itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><p>&#8220;For quality control of chemical libraries, 1D NMR spectra are acquired under full automation from 384-well plates on as many as 130 compounds within 24 hours using 128 scans per spectrum and a sample-to-sample cycle time of about 11 min. Because of the low volume requirements and high mass sensitivity of the microflow NMR system, 30 nmol of a typical small molecule is sufficient to obtain high quality, well-resolved, 1D proton or 2D COSY NMR spectra in approximately 6 or 20 min of data acquisition time per experiment, respectively.&#8221;<\/p>\n<p>&#8220;Because of the high mass sensitivity and low sample consumption of the One-Minute microflow NMR system, and because it can use D2O or nearly any solvent while still being economical, the automated microflow system described and characterized here also has great potential for metabolite evaluation, and other applications of biological interest.&#8221;<\/p>\n<\/div><div class='avia-testimonial-meta'><div class='avia-testimonial-arrow-wrap'><div class='avia-arrow'><\/div><\/div><div class='avia-testimonial-meta-mini'><strong  class='avia-testimonial-name'    itemprop=\"name\" >Bernhard Geierstanger<\/strong><span  class='avia-testimonial-subtitle '    itemprop=\"jobTitle\" >Genomics Institute of the Novartis Research Foundation, Analytical Chemistry, 2005<\/span><\/div><\/div><\/div><\/div>\n<div class='avia-testimonial av_one_full flex_column no_margin avia-testimonial-row-1 '  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/Person\" ><div class='avia-testimonial_inner'><div class='avia-testimonial-content '    itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><p style=\"color: #000000; font-family: Tahoma, Verdana; font-size: 11px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: auto; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px;\" align=\"LEFT\"><span style=\"color: #666666; font-family: Arial; font-size: small;\">&#8220;The active volume of the flow cell is 3\u00b5L, compared with 0.5 mL in a conventional probe. \u2018The procedure is different but very simple,\u2019 said Schroeder. \u2018Capillary NMR offers similar sensitivity to cryo probes but at considerably lower cost and without the technically challenging cryo support system of supercooled helium gas. Further design refinements will lead to additional sensitivity increases.'&#8221;<\/span><\/p>\n<p style=\"color: #000000; font-family: Tahoma, Verdana; font-size: 11px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: auto; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px;\" align=\"left\"><span style=\"font-family: Arial; font-size: small;\"><span style=\"color: #666666;\">Frank Schroeder, <\/span><span style=\"font-family: Arial; font-size: small;\"><span style=\"color: #666666;\">Cornell University,<\/span><\/span><br \/>\n<span style=\"color: #3333cc;\"><i><b>Royal Society of Chemistry: Chemistry World<\/b><\/i><\/span><b>,<\/b><span style=\"color: #666666;\">July 25, 2005<\/span><\/span><\/p>\n<\/div><div class='avia-testimonial-meta'><div class='avia-testimonial-arrow-wrap'><div class='avia-arrow'><\/div><\/div><div class='avia-testimonial-meta-mini'><strong  class='avia-testimonial-name'    itemprop=\"name\" >Frank Schroeder<\/strong><span  class='avia-testimonial-subtitle '    itemprop=\"jobTitle\" >Cornell University, Royal Society of Chemistry: Chemistry World,July 25, 2005<\/span><\/div><\/div><\/div><\/div>\n<\/section><\/div><\/p><\/div><div class=\"flex_column av_one_third  flex_column_div   \" ><p><div class='avia-builder-widget-area clearfix '>        <div id=\"wpdm_newpacks_widget-4\" class=\"widget clearfix widget_wpdm_newpacks_widget\">        <h3 class=\"widgettitle\">New Downloads<\/h3><div class='w3eden'><\/div><\/div><\/div><br \/>\n<div class='avia-builder-widget-area clearfix '><div id=\"xyz_insert_html_widget-2\" class=\"widget clearfix widget_xyz_insert_html_widget\"><h3 class=\"widgettitle\">.<\/h3><script type='text\/javascript' charset='utf-8'>\r\n  var vcHost = document.location.protocol == \"https:\" ? \"https:\" : \"http:\";\r\n  document.write(unescape(\"%3Cscript src='\" + vcHost + \"\/\/www.vcita.com\/widgets\/active_engage\/9055af7567f66f3c\/loader.js' type='text\/javascript'%3E%3C\/script%3E\"));\r\n<\/script><\/div><\/div><\/p><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":54,"parent":227,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":[],"_links":{"self":[{"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=\/wp\/v2\/pages\/181"}],"collection":[{"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=181"}],"version-history":[{"count":18,"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=\/wp\/v2\/pages\/181\/revisions"}],"predecessor-version":[{"id":1966,"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=\/wp\/v2\/pages\/181\/revisions\/1966"}],"up":[{"embeddable":true,"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=\/wp\/v2\/pages\/227"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=\/wp\/v2\/media\/54"}],"wp:attachment":[{"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=181"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}