{"id":1067,"date":"2014-06-07T16:27:08","date_gmt":"2014-06-07T16:27:08","guid":{"rendered":"http:\/\/protasis.net\/blog2014\/?page_id=1067"},"modified":"2014-06-23T07:41:23","modified_gmt":"2014-06-23T07:41:23","slug":"instrument-upgrades","status":"publish","type":"page","link":"http:\/\/protasis.net\/blog2014\/?page_id=1067","title":{"rendered":"What&#8217;s New"},"content":{"rendered":"<div class=\"flex_column av_two_third  flex_column_div first  \" ><section class=\"av_textblock_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock '   itemprop=\"text\" ><h2>Winter 2014 Customer Support Letter<\/h2>\n<p>March 11, 2014<\/p>\n<p><strong><em>Re:\u00a0 Keep your CapNMR probe and automation system running at factory specifications with Uptime Support!<\/em><\/strong><\/p>\n<p>Dear Customer:<\/p>\n<p>Brrrr!\u00a0 It is that time of year.\u00a0 The snow and the cold have been deep.\u00a0 Let\u2019s add another log to the fire and plan for a productive 2014.\u00a0 We\u2019ll get you started on the coldest mornings!<\/p>\n<p>We would like to start by checking on the status of your equipment with a short phone call and also learn more about how you are using CapNMR and\/or One-Minute NMR in your laboratory.\u00a0 We have some customers running hundreds of CapNMR samples every week and others that only run a few \u2018precious\u2019 samples each month, as they isolate new molecules from nature.\u00a0 We can possibly help you by sharing information about how other customers are getting the most use out of their probes and automation system.\u00a0 In particular, we can help you scale down your procedures to save sample, solvent and magnet time.<\/p>\n<p>We have also summarized our understanding of your current configuration and readiness condition using a new customer support web site. We have created an account for you on the web site that contains basic information about your existing CapNMR probe and\/or automation systems.\u00a0 In the \u2018Recommended For You\u2019 box, we have listed our suggested support plan options and made recommendations for potential upgrades to your system based upon our newest capabilities.\u00a0 Many of our customers prefer to budget ahead for routine support (and we believe this is normally the most cost-effective choice), but we want you to know that we also provide the same exact high quality services on a \u2018per incident\u2019 basis.\u00a0 Choose the support path that works for you.\u00a0 In any case, we know that our probes and fluidics systems are capable of producing exceptional NMR spectra at the highest sample throughput in the industry and we want to keep your CapNMR and\/or One-Minute NMR systems running in top condition.<\/p>\n<p><a href=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/06\/Umbrella-001.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"alignright wp-image-1708 size-square\" src=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/06\/Umbrella-001-180x180.jpg\" alt=\"Umbrella-001\" width=\"180\" height=\"180\" srcset=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/06\/Umbrella-001-180x180.jpg 180w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/06\/Umbrella-001-80x80.jpg 80w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/06\/Umbrella-001-36x36.jpg 36w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/06\/Umbrella-001-120x120.jpg 120w\" sizes=\"(max-width: 180px) 100vw, 180px\" \/><\/a>Our <strong><em>Silver Level \u2013 Uptime Support Plan<\/em><\/strong> provides umbrella repairs coverage including our valuable cleaning and recertification service ANY TIME you need it.\u00a0 Most of our plan customers find that an annual tune-up and confirmation of factory specifications keeps the probe running at its original factory specification and, most importantly, provides a high level of confidence in their CapNMR detector.\u00a0 The Silver Plan also offers unlimited telephone support, software upgrades (value = $3750\/yr.), access to special web tutorials and our convenient consumables kit (so you always have the right parts on hand, value ~ $500.).\u00a0 We believe an <em>Uptime Support Plan <\/em>is a well-balanced investment.<\/p>\n<p>This year, we are also re-introducing our <strong><em>Gold Level \u2013 Uptime Support Plan<\/em><\/strong> after proving this program for a year at Novatia, LLC.\u00a0 \u2018Go for the Gold\u2019 and we will build a backup probe for your system and make it available (by Air Freight) as a loaner if your primary probe needs repair or cleaning services.\u00a0 We added this service for customers in, (1) large departments with many users and\/or (2) high throughput laboratories with many samples that need the highest level of uptime available.\u00a0 Additionally, this premium plan includes Priority Response, an annual on-site Preventive Maintenance visit, Operator re-Training (on-site during PM or at our CapNMR school) and our unique Application Forum that provides direct access to industry experts\u2014plus all of the services in our Silver Level plan.\u00a0 We believe this is best support plan in our industry.\u00a0 These ten elements combine to weave a security blanket of premium service that keeps your equipment running with the highest level of performance and uptime and provides you with quiet confidence.<\/p>\n<p>A discussion of our Customer Support would not be complete without acknowledging the Protasis staff.\u00a0 You work directly with these hard-working scientists and see the extra effort they expend to complete our comprehensive installation and training sessions on the front-end and to support you every day.\u00a0 Help us help you by subscribing to our <em>Silver-<\/em> or <em>Gold-Level Uptime Support Plan<\/em>.<\/p>\n<h3>New Offerings\/Upgrades for 2014<\/h3>\n<p><strong><em>Windows 8 Upgrade for USPY customers.<\/em><\/strong>\u00a0 One-Minute NMR was developed on Windows XP platforms.\u00a0 A decade later, Microsoft has moved on to improved tools and now you can too!\u00a0 Upgrade to our Windows 8 (or Windows 7, if your company prefers it) and you\u2019ll run faster and achieve new levels of performance and security.\u00a0 This upgrade is free to Uptime Support Plan customers.\u00a0 Subscribe for two years or more and we\u2019ll also upgrade your Instrument Server for FREE!\u00a0 You\u2019ll get a new mainboard with faster CPU, more RAM and a new, larger hard drive.<\/p>\n<p><strong>Expanded Kit Offerings on The microNMR Outlet.<\/strong>\u00a0 We have posted our installation and consumable kits on a new online store at <a href=\"http:\/\/www.protasis.net\/catalog\">http:\/\/www.protasis.net\/catalog<\/a>.\u00a0 The contents of each kit are listed in the bundle and separately.\u00a0 You can order these items online using Paypal or purchase order.\u00a0 Microfluidic systems work best with the correct parts.\u00a0 We\u2019ll show you our recommendations with pictures, diagrams and tutorials on the web site itself and with service notes that you can download.\u00a0 Already have some parts on hand?\u00a0 The store lets you unbundle the USPY kit and make substitutions.<\/p>\n<p><strong>Automate your existing CapNMR probe.\u00a0 <\/strong>Still loading your CapNMR probe one \u2018precious\u2019 sample at a time?\u00a0 Then you are getting good results&#8211;manual syringe loading is still <em>sensitivity, simplicity and economy<\/em> at its very best.\u00a0 But you could get even more results overnight or over the weekend by adding one of our semi- or fully-automated sample loaders.\u00a0 Have a CTC\/LEAP liquid handler we could redeploy?\u00a0 That is a good start and would get you running at a significant cost savings.\u00a0 Look for a used HTC or HTS PAL in good condition and we\u2019ll give it new life.<\/p>\n<p><strong>Run plates and vials directly on your cryoprobe.<\/strong>\u00a0 Did you know you can run microplates or vial racks on your Bruker cryoprobe or Agilent cold probe?\u00a0 One-Minute NMR is now compatible with flowcell inserts that you can easily drop into your cryo- or cold-probe in a few minutes.\u00a0 The inlet tubing goes all the way through the bore and comes out through a port in the VT manifold.\u00a0 The outlet tubing goes to waste or can go back to the CTC\/LEAP liquid handler for recollection.\u00a0 Bruker offers 15, 30 and 60uL active volumes with their CryoFit flow inserts.\u00a0 Agilent offers 60uL active volumes.\u00a0 Many customers already have these inserts.\u00a0 No you can use them to good advantage!<\/p>\n<p><strong><a href=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/06\/CryoFlow-60uL-Flowcell-Amgen-260W-x-638H.png\"><img decoding=\"async\" loading=\"lazy\" class=\"alignright wp-image-1709 size-medium\" src=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/06\/CryoFlow-60uL-Flowcell-Amgen-260W-x-638H-122x300.png\" alt=\"CryoFlow 60uL Flowcell - Amgen - 260W x 638H\" width=\"122\" height=\"300\" srcset=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/06\/CryoFlow-60uL-Flowcell-Amgen-260W-x-638H-122x300.png 122w, http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/06\/CryoFlow-60uL-Flowcell-Amgen-260W-x-638H.png 260w\" sizes=\"(max-width: 122px) 100vw, 122px\" \/><\/a>Get <em>Zero Dispersion Sample Loading<\/em> (ZDSL).<\/strong>\u00a0 Samples can be loaded in about two minutes using an inert fluorocarbon push liquid to displace the sample and park it in the downstream flowcell.\u00a0 The fluorocarbon is immiscible with NMR solvents so samples are moved as plugs with no dilution during transport to the flowcell.\u00a0 The result is striking!\u00a0 Zero Dispersion Sample Loading (ZDSL) provides up to two-fold increases in S\/N compared to same-solvent sample loading.\u00a0 Since concentration is maintained, this system is ideal for quantitation of library samples or biologically sensitive screening studies.\u00a0 Ask for the Amgen ENC poster.<\/p>\n<p><strong>\u00a0Want to amp your productivity?<\/strong>\u00a0 If you are in a larger departments with many users and\/or many samples, ask about our new rack pedestal (on wheels) <strong><em>Discovery NMR WorkCenter<\/em><\/strong> package with up to four independent HTSL pumps and six solvent reservoirs.\u00a0 You could use this with our newest <strong><em>CapNMR DPC (Dual Proton Carbon Flowcells) Probe<\/em><\/strong> to get twice as much work out of your existing NMR system and \u201cCut the Cost of NMR in Half.\u201d<\/p>\n<p><a href=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/nmr-01-e1400912389534.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"alignleft wp-image-569 size-medium\" src=\"http:\/\/protasis.net\/blog2014\/wp-content\/uploads\/2014\/05\/nmr-01-300x188.jpg\" alt=\"nmr-01\" width=\"300\" height=\"188\" \/><\/a>Finally, let me tell you a little about a significant achievement for Protasis and our partners in 2013.\u00a0 At the start of the year, as part of Pfizer\u2019s Strategic Alliance program, we installed the world\u2019s first <strong><em>CryoFree 200MHz HTS NMR magnet<\/em><\/strong> in an integrated, carted system for process chemists at Pfizer-Groton to use in reaction monitoring applications.\u00a0 This unique magnet requires no liquid cryogens\u2026 ever!\u00a0 Flip one switch to cool down the magnet (to 18 deg K in about 24 hours) using a standard cryo-refrigerator.\u00a0 Then flip another switch to energize the magnet in about 15 minutes.\u00a0 This compact magnet is 15\u201d in diameter (with shielding) and 15\u201d tall and is \u2018right-sized\u2019 for our CapNMR probe.\u00a0 Ask for your copy of our joint Pfizer-Protasis ENC2013 poster with all of the details!\u00a0 Additional results were also reported recently at PANIC in Charlotte in February and SciX in Milwaukee in September.<\/p>\n<p>Let me know a good time for a brief call to review your instrument status and answer any questions about your system.\u00a0 Please take a look at the web site (at <a href=\"http:\/\/www.protasis.net\/catalog\">http:\/\/www.protasis.net\/catalog<\/a>) and let us know how you like the new store\u2014we\u2019re still making changes, so tell us about any items you would like us to add\u2014it is intended to become a combination of an \u2018information repository\u2019 and a \u2018part\/support\/consumables\u2019 store in one web site.\u00a0 We\u2019ll work with you to update the details on your configuration.\u00a0 It will include the latest Instrument Status and Customer Recommendations reports for your system.\u00a0 Send us some service photos of the front and back and closeups of your system and we will post them for easy reference.<\/p>\n<p>Also, please let us what is new in your world.\u00a0 Any recent publications?\u00a0 Great looking spectra?\u00a0 We would like to show some of your recent results in our ENC booth in Boston in March.<\/p>\n<p>Best regards,<\/p>\n<p>Dave<\/p>\n<\/div><\/section><\/div><div class=\"flex_column av_one_third  flex_column_div   \" ><p><div class='avia-button-wrap avia-button-center '><a href='' class='avia-button  avia-icon_select-no avia-color-theme-color avia-size-large avia-position-center '   ><span class='avia_iconbox_title' >Schedule Now<\/span><\/a><\/div><br \/>\n<div  class='hr hr-default '><span class='hr-inner ' ><span class='hr-inner-style'><\/span><\/span><\/div><br \/>\n<div class='avia-builder-widget-area clearfix '>        <div id=\"wpdm_newpacks_widget-3\" class=\"widget clearfix 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extralight-border\"><\/span><\/section><section id=\"bbp_topics_widget-3\" class=\"widget clearfix widget_display_topics\"><h3 class=\"widgettitle\">Recent Topics<\/h3>\n\t\t<ul>\n\n\t\t\t\n\t\t\t\t<li>\n\t\t\t\t\t<a class=\"bbp-forum-title\" href=\"http:\/\/protasis.net\/blog2014\/?topic=windows-xp-end-of-life\">Windows XP End of Support<\/a>\n\n\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t<\/li>\n\n\t\t\t\n\t\t<\/ul>\n\n\t\t<span class=\"seperator extralight-border\"><\/span><\/section><\/div><\/p><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":1047,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":[],"_links":{"self":[{"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=\/wp\/v2\/pages\/1067"}],"collection":[{"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1067"}],"version-history":[{"count":9,"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=\/wp\/v2\/pages\/1067\/revisions"}],"predecessor-version":[{"id":1711,"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=\/wp\/v2\/pages\/1067\/revisions\/1711"}],"up":[{"embeddable":true,"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=\/wp\/v2\/pages\/1047"}],"wp:attachment":[{"href":"http:\/\/protasis.net\/blog2014\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1067"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}