Protasis/MRM introduces the next generation in CapNMR detection with a new family of MultiFlow Probes, the Dual FlowCell (DFC) model. Each detector in the DFC probe delivers the same great resolution and S/N as single flowcell CapNMR probes, but with a doubling of capacity.
The excellent electrical isolation and magnetic materials match between the two detectors allows the DFC probe to be used in a variety of different detection modes. Both radiofrequency microcoils can be shimmed to high resolution simultaneously for parallel mode data acquisition. Alternatively, individual shim settings are readily called via subroutine to enable serial mode operation.
The Protasis MultiFlow DFC probes come in a variety of configurational flavors and can be tailored to your specific application needs. Presently Protasis offers the option of 5 μL and 10 μL sizes for each of the two flowcells, in the popular indirect carbon with zgradient ICG) configuration (1H/2H{13C} with z-directed gradient). Each of the independent flowcell circuits has an independent z-gradient that is controlled through the Protasis Signal Router box. Frequency lock is provided on the lower detector only, and serves to maintain both flowcells in lock with the B0 field, provided that at least a 10% deuterated solvent is utilized in the upper flowcell. We are always interested in hearing requests for novel configurations to meet new application needs.